Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | Clarithromycin |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 81103-11-9 | Mf: | C38H69NO13 |
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MW: | 747.953 | Specification: | 99% |
EINECS: | / | Appearance: | White Crysatlline Powder |
Sample: | Available | ||
High Light: | 99% Clarithromycin Powder,CAS 81103-11-9 Antibiotic API,Antibiotic Clarithromycin Powder |
CAS 81103-11-9 99% Clarithromycin Powder API Antibiotic
Product name |
Clarithromycin |
Appearance |
White Crystalline Powder |
CAS |
81103-11-9 |
MF |
C38H69NO13 |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of Clarithromycin
Clarithromycin is a derivative of erythromycin, which was successfully developed by Japanese Dazheng Company in the early 1990s and registered under the trade name Clarith. Later, Dazheng first transferred its technology to Abbott for production. In 1990, it was listed in Ireland and Italy. In October 1991, it was approved by FDA to be listed as a new IB drug under the trade name of Biaxin. In 1993, it was listed in Hong Kong, China under the trade name of Klacid. In Europe and Asia, it was listed in more than 50 countries around the world under the trade name of Klaxin. The market usage has steadily increased and has played an important role in clinical practice. Clarithromycin and its tablets, as well as granules, dispersible tablets, sustained-release tablets, injections and dry suspensions currently produced.
The Application & Function of Clarithromycin
The product belongs to 14 membered macrolide antibiotics.
The antibacterial spectrum is the same as erythromycin, roxithromycin, etc., but the antibacterial effect on gram-positive bacteria such as streptococcus, pneumococcus, staphylococcus is slightly better, and it also has certain antibacterial activity on induced erythromycin resistant strains.
Clarithromycin and its metabolites in vivo have enhanced antibacterial effect on influenza bacillus. The product also has certain effects on gonococcus, listeria and campylobacter jejuni, while it has stronger effects on legionella pneumophila, mycoplasma pneumoniae, chlamydia trachomatis, ureaplasma urealyticum, etc. than erythromycin, and plays a prominent role in new varieties developed in recent years, MIC90 is about 0.008-0.12mg/L.
In addition, it has certain activity to Spirochaeta, Mycobacterium avium and Toxoplasma muris, and most of them are superior to other varieties. In addition to the strong antibacterial effect on anaerobic bacteria, the effect on Bacteroides fragilis is better than that on erythromycin and other antibiotics such as Staphylococcus aureus, Streptococcus pyogenes, and Influenza bacteria.
This drug belongs to macrolide antibiotics. Its mechanism is to inhibit the synthesis of proteins by blocking the binding of 50S subunits of nuclear proteins
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The COA of Clarithromycin
ITEMS OF ANALYSIS | SPECIFICATION | RESULT |
Characteristics | White crystalline powder, odorless or practically odorless and practically tasteless | Complies |
Identification | IR: The infrared absorption spectrum should be concordant with the reference spectrum | Complies |
Solubility | Soluble in ethanol, chloroform, almost insoluble in water. | Complies |
Water | ≤4.0% | 1.5% |
Assay | 99% | 99.80% |
Conclusion | Conform with the standard |
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