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API Pharmaceutical anti inflammation drugs CAS 95382-33-5 omeprazole magnesium

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Omeprazole Magnesium
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 95382-33-5 Mf: C17H19MgN3O3S
MW: 713.12 Specification: 99%
Einecs No.: 201-212-8 Appearance: White Granules
Sample: Available Whatsapp: +86152 029 61574

Product Description

API Pharmaceutical anti inflammation drugs CAS 95382-33-5 omeprazole magnesium

API Pharmaceutical anti inflammation drugs CAS 95382-33-5 omeprazole magnesium 0

Product name

OMEPRAZOLE MAGNESIUM

Appearance

White granules

CAS

95382-33-5

MF

C17H19MgN3O3S

Purity

99%

Storage

Keep in cool dry place.

API Pharmaceutical anti inflammation drugs CAS 95382-33-5 omeprazole magnesium 1

Whatsapp: +86 152 029 61574

The Introductction of OMEPRAZOLE MAGNESIUM

 

Omeprazole Magnesium is an antacid over-the-counter drug. It specifically acts on the site of the proton pump in the gastric wall cell and is converted into the active form of sulfenamide, which then irreversibly binds to the sulfhydryl group of the proton pump through the disulfide bond to produce a complex of sulfenamide and the proton pump (H+-K+-ATPase), thereby inhibiting the activity of the enzyme and preventing the transport of H+ from the wall cell into the gastric lumen, blocking the last step of gastric acid secretion, which can greatly reduce the amount of gastric acid in the gastric juice.


Omeprazole Magnesium has a strong and long-lasting inhibitory effect on gastric acid secretion caused by a variety of causes (e.g., basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin and stimulation of the vagus nerve, including gastric acid secretion caused by dibutyl cyclic adenosine acid that cannot be inhibited by H2 receptor blocking drugs).


Omeprazole Magnesium is used clinically to treat peptic ulcer, reflux esophagitis, Zollinger-Ellison syndrome, and eradication of Helicobacter pylori (HP) with satisfactory results.


However, it should be noted that excessive use of acid-suppressing drugs such as Omeprazole Magnesium can lead to a decrease in the concentration of gastric acid and weakened acidity, then the germs that enter the stomach may not be killed and enter the intestine, doubling the risk of intestinal infection with germs, then diarrhea is possible. Because of the lowered stomach acid affects digestion, which in turn affects the intestinal absorption of calcium, iron and other trace elements and vitamins, leading to calcium deficiency in the body and susceptibility to fractures.

 

The Application & Function of OMEPRAZOLE MAGNESIUM

 

1. Omeprazole Magnesium is used for gastric and duodenal ulcers, stress ulcers, etc.

2. Omeprazole Magnesium is used for reflux esophagitis and gastrinoma.

3. Omeprazole Magnesium injection can also be used for.
   ①Gastrointestinal bleeding, such as peptic ulcer bleeding, anastomotic ulcer bleeding, etc., and prevention of upper gastrointestinal bleeding caused by serious diseases (such as cerebral hemorrhage, severe trauma, etc.) and after gastric surgery.
   ②Acute gastric mucosal injury that is complicated during stressful conditions or caused by NSAIDs.
   ③Patients under general anesthesia or after major surgery and coma to prevent gastric acid reflux and aspiration pneumonia.

4. Omeprazole Magnesium with amoxicillin and clarithromycin, or in combination with metronidazole and clarithromycin, can effectively kill Helicobacter pylori (Hp).

 

Other Name of OMEPRAZOLE MAGNESIUM: (S)-omeprazole magnesium; Omeprazole magnesium; GASTROGARD; OMEPRAZOLE Mg; Loec; Moprial; Omeprazolum; Magnesium,bis[6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, (T-4); 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (2:1); Magnesium bis(5-methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide)

 

The COA of OMEPRAZOLE MAGNESIUM

 

Product OMEPRAZOLE MAGNESIUM Batch No 20210915
Date of Manufacture 2021-09-15 Quantity 500kg
Date of Certificate 2021-09-16 CAS No. 95382-33-5
Date of Expire 2023-09-14 Sample 10g
Storage Store in cool & dry place, in well-closed containers.
Test Items Specification Results
Appearance White Granules Conforms
Identification

Infrared absorption:

Must similar to reference standard

Conforms
 

Ultraviolet absorption:

Must similar to reference standard

Conforms
  Test for potassium: Must be positive Conforms
Water ≦ 0.5% 0.2%
Loss on drying ≦ 0.5% 0.35%
Residue on Ignition ≦ 0.2% 0.06%
Chromatographic purity Any individual impurity ≦ 0.2% 0.03%
Total impurities ≦ 0.5% 0.07%
Heavy metals ≦ 10 ppm Conforms
Residual solvents Cyclohexane ≦ 0.1% 0.003%
Isopropyl alcohol ≦ 0.2% 0.05%
Assay 98.5%~101.0% 99.3%
Conclusion Complies with USP30 standards.

Contact Details
Gary Liu

Phone Number : +8615202961574

WhatsApp : +8618629242069