Name: | Diphenhydramine Hcl Powder | CAS: | 58-73-1 |
---|---|---|---|
MF: | C17H21NO | Whatsapp: | +86152 029 61574 |
Veterinary API Diphenhydramine HCL powder
Product name | Diphenhydramine |
Appearance: | white or nearly white crystalline powder |
MF | C17H21NO |
Laboratory | 99.0%-101.0% |
Shelf life | 2 years |
Diphenhydramine hydrochloride is an antihistamine drug having the chemical name 2-(Diphenylmethoxy)- N,N-dimethylethylamine hydrochloride. It occurs as a white, crystalline powder, is freely soluble in water and alcohol .
Diphenhydramine hydrochloride in the parenteral form is a sterile, pyrogen-free solution available in a concentration of 50 mg of diphenhydramine hydrochloride per mL. The solutions for parenteral use have been adjusted to a pH between 5.0 and 6.0 with either sodium hydroxide or hydrochloric acid and contains 0.1 mg/mL benzethonium chloride as a germicidal agent.
Diphenhydramine is an H1-histamine receptor antagonist. Diphenhydramine is classified as an antihistamine; sedative and hypnotic.
The parenteral form of diphenhydramine hydrochloride is a sterile, pyrogen-free solution with a concentration of 50 mg diphenhydramine hydrochloride per milliliter. The parenteral solution has been adjusted to a pH between 5.0 and 6.0 with sodium hydroxide or hydrochloric acid, and contains 0.1 mg/mL benzethonium chloride as a bactericide.
Function
1.Can eliminate all kinds of allergy symptoms.Its central inhibitory effect is significant, but not as good as promethazine hydrochloride;Still have sedative.
2.Prevent dizzy move and antiemetic effect, also have fight choline effect.
Items
|
Specification
|
Results
|
Appearance
|
White or almost white crystalline powder
|
Complies
|
Solubility
|
Very soluble in water,freely soluble in alcohol
|
Complies
|
Identification
|
UV
|
Complies
|
|
IR
|
Complies
|
|
It responds to the tests for chloride
|
Complies
|
Melting range
|
168-172°C
|
168-169°C
|
Appearance of solution
|
Clear, NMTBY6
|
Complies
|
Acidity or alkalinity
|
NMT 0,5ml ofO.OlM NaOH
|
Complies
|
Related substance
|
Impurity A: 0.5% max
|
0.04%
|
|
Any other unspecified impurity: 0.3% max
|
Not Detected
|
|
Total impurities: 1.0% max
|
0.04%
|
Loss on drying
|
0.5% max
|
0.2%
|
Sulphated ash
|
0.1% max
|
0.04%
|
Assay(Dried substance)
|
99.0^101.0%
|
100.8%
|
Residual solvent
|
Ethanol: 0.5% (5000ppm) max
|
0.03%
|
|
Toluene: 0.089% (890ppm) max
|
0.0004%
|