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Ivermectin 99% Veterinary API CAS 70288-86-7 antibiotic antiparasitic drug

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Ivermectin
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually 7-10days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 70288-86-7 Mf: C48H74O14
MW: 875.09 Specification: 98%-99%
Einecs No.: 274-536-0 Appearance: White Or Yellowish-white Crystalline Powder
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99% Ivermectin Veterinary API


CAS 70288-86-7 Veterinary API


Antibiotic Ivermectin Powder

Product Description

Ivermectin 99% Veterinary API CAS 70288-86-7


Product Name Ivermectin
CAS 70288-86-7
Molecular formula C48H74O14
Molecular weight 875.09300
Grade Pharmaceutical Grade
Color White powder
Purity 99%
Shelf life 2 years



The Introductction of Ivermectin:


        Ivermectin is a new broad-spectrum, high-efficiency, low-toxicity antibiotic antiparasitic drug, which has a good killing effect on internal and external parasites, especially nematodes and arthropods. But it is ineffective against tapeworms, flukes and protozoa. The repelling effect of macrolide antiparasitic drugs on nematodes and arthropods is to increase the release of the inhibitory transmitter γ-aminobutyric acid (GABA) of the worms, and to open the Cl ion channel controlled by glutamate, Enhance the permeability of the nerve membrane to Cl, thereby blocking the transmission of nerve signals, eventually nerve paralysis, so that muscle cells lose the ability to contract, resulting in the death of the worm.


English name: Ivermectin
English alias: Ivermecti;mk933;22,23-dihydroavermectin B1;Uvemec;Ivosint;Ivermectin;EQVALEN;IVOMEC;
CAS number: 70288-86-7
Molecular formula: C48H74O14
Molecular weight: 875.09300
Exact Mass: 874.50800
PSA: 170.06000


The Application & Function of Ivermectin:


1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to semisynthetic broad-spectrum resistant parasites.
2. Ivermectin has effect for most of the various life cycle nematodes.
3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus.
4. Ivermectin has effect for dung round worms that is only stay in intestinal tract.
5. Ivermectin has selective inhibition.
6. Ivermectin can not go through the blood brain barrier of humanbeings.


In veterinary medicine ivermectin powder is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.

Ivermectin is widely used in gastrointestinal nematodes, lung nematodes and parasitic arthropods of cattle, sheep, horses and pigs, intestinal nematodes in dogs, ear mites, scabies mites, heartworms and microfilariae, and poultry stomach Gut nematodes and ectoparasites.


This product is a derivative of avermectin, which is an oral semi-synthetic broad-spectrum antiparasitic drug. This product is effective against most (but not all) nematodes of various life cycles; it is effective against microfilariae of Onchocerciasis, but not adults; it is also effective against strongyloides only in the intestinal tract. This product has a selective inhibitory effect. It binds with high affinity to chloride ion channels with glutamate as the valve in the nerve cells and muscle cells of non-vertebral animals, resulting in an increase in the permeability of the cell membrane to chloride ions, causing nerve cells or muscles. The cells hyperpolarize, paralyzing or dying the parasite. It also interacts with chloride channels of other ligand valves, such as the neurotransmitter g-aminobutyric acid (GABA). The selectivity of this product is due to the absence of glutamate-chloride channels in some mammals and the low affinity of abamectin for mammalian ligand-chloride channels. This product cannot penetrate the human blood-brain barrier. Onchocerciasis and strongyloidiasis and hookworm, roundworm, whipworm, pinworm infection.




Ivermectin 99% Veterinary API CAS 70288-86-7 antibiotic antiparasitic drug 0


The COA of Ivermectin:


Tests Specification Results
Appearance White or yellowish-white crystalline powder, slightly hygroscopic. Yellowish-white crystalline powder, slight hygroscopic.
Solubility Practically insoluble in water, freely soluble in methylene chloride, soluble in alcohol. Qualified
Identification IR Corresponds to that of CRS standard Qualified
HPLC The retention time for H2Bla and H2Blb in the chromatogram obtained with the test solution corresponds to those of standard preparation Qualified
Appearance of solution Clear and not more intensely colored than BY? Clear
Specific optical rotation (anhydrous and solvent-free substance), ° -20--17 -17.9
Related substances (%) Individual impurity(RRT 1.3-1.5)≤2.5 I-l:<0.05 K:2.1
Any other impurity ≤ 1 C:0.06 A:0.57
J:0.14 H:0.39 D:<0.05 F:<0.05
E:0.36 1-2:0.19
Total ≤5 3.8
Disregard limit: 0.05
Ethanol and Formamide (%) Ethanol ≤5.0 3.9
Formamide≤3.0 2.5
Catalyst (ug/g) ≤1 <1
Water (%) ≤1.0 0.26
Sulphated ash (%) ≤0.1 0.07
Heavy Metal (%) ≤0.002 <0.002
Assay (%) (HPLC, on dry basis) H2Bla/(H2Bla +H2Blb)≥90.0 97.7
95.0≤H2Bla +H2Blb≤ 102.0 96.7
Conclusion Complies with the requirements of EP10.0


HNB Biotech company details


Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian
International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the
leading researcher and one of the biggest manufacturer in high technology API area.
There are 8 experts in our research team. We insist in innovation and produce high quality
products. And GMP standard workshop and complete stainless extraction equipment.
We have 2 sales departments over 20 people and sell our products all over the world.
We also have strong professional research and development team, talented personnel and
completely equipped laboratory for the quality controlling. Various Detection Device is
equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto
titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
HNB mainly engaged in export of products including, without limitation, pharmaceutical raw
materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant
extract, feed and food additives.
Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and
Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends
from both home and abroad.
Passion to innovate, Power to deliver !
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Contact Details

Phone Number : +8618292978289

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