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Antipyretic Analgesic 99% CAS 148553-50-8 Pregabalin Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO9001
Model Number: Pregabalin
Minimum Order Quantity: 1kg
Price: 280USD/kg
Packaging Details: 1.1kg/bag;25kg/drum 2. Inside: steril plastic bag+aluminum foil bag Outside: carton/drum
Delivery Time: 3-7days
Payment Terms: T/T, ,, L/C, D/A, D/P
Supply Ability: 10Metric tons per month
Detail Information
Product Name: Pregabalin Appearance: White Crystalline Powder
CAS No.: 148553-50-8 Molecular Formula: C8H17NO2
Shelf Life: 24months When Properly Stored Purity: 99%min
HS Code: 2915900090 Function: Antiepileptic And Anticonvulsant
Storage Condition: Keep Away From Heat, Open Flames And Sparks. Whatsapp: +86152 029 61574
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99% Pregabalin Powder


Pregabalin Powder Antipyretic Analgesic


CAS 148553-50-8 Antipyretic Analgesic

Product Description

Antipyretic Analgesic 99% CAS 148553-50-8 Pregabalin Powder

Antipyretic Analgesic 99% CAS 148553-50-8 Pregabalin Powder 0

Wahtsapp/wechat: +86 152029 61574

Product Introduction

Pregabalin, chemical name (S) -3-aminomethyl-5-methylhexanoic acid, molecular formula is C8H17NO2, is an antiepileptic drug, clinical mainly for the treatment of post-herpetic neuralgia.

Pregablin is an analogue of the neurotransmitter gamma-aminobutyric acid (GABA), marketed under the brand name Lyrica. In December 2004, the FDA approved pregablin as a treatment for diabetic neuroalgia and herpes zoster neuroalgia Pregabalin was the first drug approved in both the United States and Europe for the treatment of both types of pain. In June 2005, pregabalin was approved in the European Union for the treatment of generalized anxiety disorder (GAD) and social anxiety disorder (SAD) in March 2006. Pregabalin has a good therapeutic effect on epilepsy, various animal epilepsy model studies show that pregabalin can significantly prevent seizures, its active dose is 3-10 times lower than gabapentin. Studies have found that pregabalin can reduce the sensation of toe tip stimulation and motor spinal reflex, reduce diabetes in rats Pregabalin may have advantages when used in combination with opioids. Pregabalin may provide a new option for the clinical treatment of neuropathic pain At the same time, due to the lack of clinical experience in the application of this drug and the lack of large-scale multi-center clinical studies reported in China, it is necessary to pay close attention to the efficacy and related side effects of the use of pregabalin, and actively carry out pain reassessment and other relevant indicators of the examination, and strengthen the follow-up of patients

The affinity between pregabalin and α2-δ sites (a voltage-gated calcium channel auxiliary subunit) in central nervous system tissues is high, although the mechanism of action of pregabalin is not fully understood However, modified mouse results and studies of structurally-similar compounds such as gabapentin suggest that binding of pregabalin to α2-δ is associated with pain inhibition and antiepileptic effects in animal models Pregabalin is a structural analogue of the inhibitory neurotransmitter γ -aminobutyric acid (GABA), which is not directly related to GABAA Binding of GABAB or benzodiazepine receptor did not enhance the response of GABAA in cultured neurons and did not change the concentration of GABA in rat brain, which had a temporary effect on the reuptake and degradation of GABA Cultivation of neurons, however, long-term exposure to pregabalinpregabalin increased the concentration of GABA transporters, and improve the transfer efficiency of GABA pregabalin won't block sodium channels, has no effect on the receptors, can not influence the activity of an enzyme called cyclooxygenase Pregabalin for serotonin and dopamine receptor inactive effect, to serotonin Dopamine and norepinephrine reuptake were not inhibited


Pregabalin is a γ -aminobutyric acid (GABA) analogue, similar in structure and action to gabapentin, with anti-epileptic, analgesic and anti-anxiety activities. The mechanism of antiepileptic action of pregabalin is still unclear. In laboratory studies, pregabalin showed anticonvulsant activity in various epileptic models; The activity profile of animal models was similar to that of gabapentin, but pregabalin was 3-10 times more active than gabapentin

Antipyretic Analgesic 99% CAS 148553-50-8 Pregabalin Powder 1

Product analysis report

CAS number 148553-50-8 Product Name Pregabalin
Manufacture Date: 24th Nov.,2021 Analysis Date: 24th Nov.,2021
Batch NO.: HNB211124-1 Test sample: 200gram
Storage: Store in cool&dry place, in well-closed containers.
Shelf life: 24 Months when properly stored.


Appearance White off-white crystalline powder Complies
Assay 98.0%-102.0% 99.2%

The retention time of the major peak in the chromatogram of theAssay prepration corresponds to that in the

chromatogram of the standard preparation,as obtained

in the assay

Specific rotation Between -28.6°and -35.0°, measured at 20° -32.8°
Water NMT 0.5% 0.12%
Residue on ignition NMT 0.2% 0.11%
Heavy metals NMT 0.001% Complies
Related compounds by hplc

Fructose not more than 0.3% Compound

A not more than 0.3% Other individual

impurity not more than 0.1%

Total impurities not more than 0.5%

Fructose: 0.03% Compound A: 0.04%

Total impurities:


Particle size 90% less than 350 microns Complies
Limit of sulfamate and sulfate

Sulfamate ion not more than 0.10%

Sulfate ion not more than 0.10%

Residual Solvent Methylene Chloride not more than 250μg/g Not detected
Acene not mor than 2500μg/g
Isopropanol not more than 5000μg/g
Ethanenitrile not more than 400μg/g
n-hexane not more than 290μg/g
Ethyl Acetate not more than 2500μg/g
Pyridine not more than 100μg/g
Conclusion Conform with the Standard

Antipyretic Analgesic 99% CAS 148553-50-8 Pregabalin Powder 2

Competitive Advantages

1.Golden Manufactory under ISO/GMP with large stock.
2.We offer high quality products at competitive price.
3.Shortest delivery time.
4.Flexible payment terms.
5.Timely after-sale service.
6.International Authorized Third-Party Test For The Products You Demand.
7.Our products have been exported to USA, Japan, Germany, France, United Kingdom, Italy, Brazil, Canada, Russia,Turkey,South Korea,French,Thailand,Malaysia,Spain and many other countries.



1.Can I get samples for testing?

Yes,sample can be provided,but you will need to pay the freight.


2.What's the delivery leadtime?
3-7 days by air after payment, if it is by sea, the shipment time should be determined according to the shipping date.
3.Do you accept customized or OEM service?
OEM service: capsules, tablets and packaging powder for retail. Detailed package, private label is available for large order, above 10,00 Pieces/bottles.
4.What’s your standard & documents?
Normally, our product standard is basis on USP, EP, CP or Enterprise standard. GMP, ISO, COA, MSDS, DGM, form A and so on has been passed. We have good quality control.
5.Are you a manufacture?
Yes, we are manufacture, pictures, vedios, docs can be provided. Welcome to visit our factory.

Contact Details
Gary Liu

Phone Number : +8615202961574

WhatsApp : +8618629242069