|Place of Origin:||China|
|Model Number:||Procaine hydrochloride|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order|
|Einecs No.:||200-077-2||Appearance:||White Crystalline Powder|
API Procaine Hydrochloride Powder,
Procaine Hydrochloride Powder 99%,
API Pharmaceutical CAS 59-46-1
HNB Supply CAS 59-46-1 Procaine Hydrochloride 99% Powder for sell
The Introductction of PROCAINE HYDROCHLORIDE
Procaine is a local anesthetic. Its hydrochloride is commonly used clinically, also known as "novocaine". White crystal or crystalline powder, easily soluble in water. Less toxic than cocaine. Add a small amount of epinephrine to the injection to prolong the action time. For infiltration anesthesia, spinal anesthesia, "closed therapy" and so on. In addition to the reactions of the central nervous system and cardiovascular system caused by overdose, allergic reactions are occasionally seen. Its metabolite, p-aminobenzoic acid (PABA), can attenuate the antibacterial efficacy of sulfonamides.
Less toxic, is one of the commonly used local anesthetics. This drug is a short-acting ester local anesthetic with low lipophilicity and weak penetration into mucosa. Generally not used for topical anesthesia, often local injection for infiltration anesthesia, conduction anesthesia, subarachnoid anesthesia and epidural anesthesia. It takes effect 1-3 minutes after injection and can be maintained for 30-45 minutes. After adding epinephrine, the maintenance time can be extended by 20%. Procaine can be hydrolyzed by esterase in plasma and converted into p-aminobenzoic acid (PABA) and diethylaminoethanol. The former can resist the antibacterial effect of sulfonamide drugs, so it should be avoided to be used with sulfonamide drugs at the same time. Procaine can also be used for partial closure of the injury site. Overdose can cause central nervous system and cardiovascular reactions. Sometimes it can cause allergic reactions, so a skin allergy test should be done before taking the drug, but allergic reactions can still occur in those with a negative skin test. Those allergic to this drug can use chloroprocaine and lidocaine instead.
① Acting on peripheral nerves, it can prevent and block the generation and transmission of nerve impulses, stabilize the membrane surface of nerve tissue, reduce the permeation of Na+, block the normal polarization and depolarization alternately, and make the transmission of nerve impulses unreasonable. , clinically known as conduction block.
② Acts on the central nervous system, generally excites first and then inhibits normal activities. The strength of the action is related to the blood concentration, which is a precursor to poisoning.
③ Acting on the cardiovascular system, a dose of intravenous injection followed by intravenous drip can restore the morbid heartbeat to normal, the effect is fast, and it is often used for rescue.