Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | fluoxe tine hydrochloride |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 59333-67-4 | Mf: | C17H19ClF3NO |
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MW: | 345.787 | Specification: | 99% |
EINECS No.: | 260-101-2 | Appearance: | White To Off-white Powder |
Sample: | Available | ||
High Light: | API Fluoxetine Hydrochloride Powder,Anti Depression Fluoxetine Hydrochloride,Pharmaceutical Fluoxetine Hcl |
Anti -depression pharmaceutical API fluoxe tine hydrochloride powder
Product name |
fluoxe tine hydrochloride |
Appearance |
White to off-white Powder |
CAS |
59333-67-4 |
MF |
C17H19ClF3NO |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of fluoxe tine hydrochloride
Fluoxe tine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Fluoxe tine inhibits the uptake of serotonin by a nerve cells (neurons) and helps people with depression, panic, anxiety, or obsessive-compulsive symptoms.
Fluoxe tine is a prescription medicine used to treat major depressive disorder, bulimia nervosa (an eating disorder), obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).
The Application & fluoxe tine hydrochloride
Fluoxe tine was shown to be effective for depression in six-week-long double-blind controlled trials, where it also alleviated anxiety and improved sleep. Fluoxe tine was better than placebo for the prevention of depression recurrence when the patients, who originally responded to fluoxe tine, were treated for a further 38 weeks. Efficacy of fluoxe tine for geriatric, as well as pediatric, depression was also demonstrated in placebo-controlled trials.
Research suggests that a significant part of the resistance to the SSRIs paroxetine (Paxil) and citalopram(Celexa) can be explained by the genetic variation of Pgp transporter. Paroxetine and citalopram, which are Pgp substrates, are actively transported from the brain by this protein. Fluoxe tine is not a substrate of Pgp, and thus a switch from paroxetine or citalopram to fluoxe tine may be beneficial to the nonresponders.
Fluoxe tine is frequently used to treat major depression, obsessive compulsive disorder, bulimia nervosa,panic disorder, body dysmorphic disorder, premenstrual dysphoric disorder, and trichotillomania. Caution should be taken when using any SSRI for bipolar disorder as this can increase the likelihood of mania; however, fluoxe tine can be used with an antipsychotic (such as quetiapine) for bipolar. It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.
Clinical application
Fluoxe tine is frequently used to treat major depressive disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder, and trichotillomania.It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.It has also been tried as a treatment for autism spectrum disorders with moderate success in adults.
Other Name of fluoxe tine hydrochloride:
Fluoxe tine HCL; Fluoxetinhydrochloride; Fluoxetin HCL; N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride (1:1); 6,11-dihydroxy-3,3-dimethyl-5-(3-methylbut-2-en-1-yl)-3,12-dihydro-7H-pyrano[2,3-c]acridin-7-one
The COA of fluoxe tine hydrochloride
Product Name: fluoxe tine hydrochloride (USP41)
CAS No.:59333-67-4
Batch No.: HNB20220808
Manufacture Date: Aug., 08th, 2022 Analysis Date: Aug., 09th, 2022 Expiry date: Aug.., 07th, 2024
Storage: Well sealed in cool and dry place
Shelf life: 24 Months when properly stored.
ITEMS | SPECIFICATIONS | RESULT |
Appearance | White either type white powder | Complies |
Identification | A,B complies with the standard | Complies |
Residue on ignition | ≤ 0.2% | 0.08% |
Organic impurities | Single impurity:≤ 0.25% | 0.13% |
Total other impurities: ≤ 0.5% | 0.22% | |
Residual solvent | Acetone ≤ 0.5% | 0.03% |
Ethanol ≤ 0.5% | 0.02% | |
Loss on drying | ≤ 0.5% | 0.3% |
Chloride | ≤ 0.09% | 0.008% |
Heavy metals | ≤ 10ppm | Complies |
As | ≤ 2ppm | Complies |
Assay(on dried basis) | 98.0%~102.0% | 99.2% |
Conclusion | This product complies with USP41 Standard |