products

Anti Depression API Pharmaceutical Fluoxetine Hydrochloride Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: fluoxetine hydrochloride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 59333-67-4 Mf: C17H19ClF3NO
MW: 345.787 Specification: 99%
EINECS No.: 260-101-2 Appearance: White To Off-white Powder
Sample: Available
High Light:

API Fluoxetine Hydrochloride Powder

,

Anti Depression Fluoxetine Hydrochloride

,

Pharmaceutical Fluoxetine Hcl


Product Description

Anti -depression pharmaceutical API fluoxetine hydrochloride powder

Anti Depression API Pharmaceutical Fluoxetine Hydrochloride Powder 0

Product name

fluoxetine hydrochloride

Appearance

White to off-white Powder

CAS

59333-67-4

MF

C17H19ClF3NO

Purity

99%

Storage

Keep in cool dry place.

 

Anti Depression API Pharmaceutical Fluoxetine Hydrochloride Powder 1

The Introductction of fluoxetine hydrochloride

 

     Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Fluoxetine inhibits the uptake of serotonin by a nerve cells (neurons) and helps people with depression, panic, anxiety, or obsessive-compulsive symptoms.
     Fluoxetine is a prescription medicine used to treat major depressive disorder, bulimia nervosa (an eating disorder), obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).

 

 

The Application & fluoxetine hydrochloride

 

Fluoxetine was shown to be effective for depression in six-week-long double-blind controlled trials, where it also alleviated anxiety and improved sleep. Fluoxetine was better than placebo for the prevention of depression recurrence when the patients, who originally responded to fluoxetine, were treated for a further 38 weeks. Efficacy of fluoxetine for geriatric, as well as pediatric, depression was also demonstrated in placebo-controlled trials.
Research suggests that a significant part of the resistance to the SSRIs paroxetine (Paxil) and citalopram(Celexa) can be explained by the genetic variation of Pgp transporter. Paroxetine and citalopram, which are Pgp substrates, are actively transported from the brain by this protein. Fluoxetine is not a substrate of Pgp, and thus a switch from paroxetine or citalopram to fluoxetine may be beneficial to the nonresponders.

Fluoxetine is frequently used to treat major depression, obsessive compulsive disorder, bulimia nervosa,panic disorder, body dysmorphic disorder, premenstrual dysphoric disorder, and trichotillomania. Caution should be taken when using any SSRI for bipolar disorder as this can increase the likelihood of mania; however, fluoxetine can be used with an antipsychotic (such as quetiapine) for bipolar. It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.

 


Clinical application

Fluoxetine is frequently used to treat major depressive disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder, and trichotillomania.It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.It has also been tried as a treatment for autism spectrum disorders with moderate success in adults.

 

Other Name of fluoxetine hydrochloride:  

 

Fluoxetine HCL; Fluoxetinhydrochloride; Fluoxetin HCL; N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride (1:1); 6,11-dihydroxy-3,3-dimethyl-5-(3-methylbut-2-en-1-yl)-3,12-dihydro-7H-pyrano[2,3-c]acridin-7-one

 

The COA of fluoxetine hydrochloride

 

Product Name: fluoxetine hydrochloride (USP41)

CAS No.:59333-67-4

Batch No.: HNB20220808

Manufacture Date: Aug., 08th, 2022 Analysis Date: Aug., 09th, 2022 Expiry date: Aug.., 07th, 2024

Storage: Well sealed in cool and dry place

Shelf life: 24 Months when properly stored.

 

ITEMS SPECIFICATIONS RESULT
Appearance White either type white powder Complies
Identification A,B complies with the standard Complies
Residue on ignition ≤ 0.2% 0.08%
Organic impurities Single impurity:≤ 0.25% 0.13%
Total other impurities: ≤ 0.5% 0.22%
Residual solvent Acetone ≤ 0.5% 0.03%
Ethanol ≤ 0.5% 0.02%
Loss on drying ≤ 0.5% 0.3%
Chloride ≤ 0.09% 0.008%
Heavy metals ≤ 10ppm Complies
As ≤ 2ppm Complies
Assay(on dried basis) 98.0%~102.0% 99.2%
Conclusion This product complies with USP41 Standard

Contact Details
Eric Tong

Phone Number : +8618220855851

WhatsApp : +8618629242069