Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | rotundine |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 10097-84-4 | Mf: | C21H25NO4 |
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MW: | 355.427 | Specification: | 99% |
Density: | 1.23 G/cm³ | Appearance: | White To Off-white Crysatlline Powder |
Sample: | Available | ||
High Light: | Rotundine Powder API Pharmaceutical,Rotundine Analgesic Powder,API Pharmaceutical CAS 10097-84-4 |
Analgesic pharmaceutical API 99% rotundine powder CAS 10097-84-4
Product name |
rotundine |
Appearance |
White to off-white Crystalline Powder |
CAS |
10097-84-4 |
MF |
C21H25NO4 |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of rotundine
Rotundine powder, an analgesic drug, has been entrapped in a PIC polysaccharide granule. It was prepared in a two-step process, i.e., first granulation of a chitosan acetated solution containing Rotundine and then complexation of the polycationic component on the granular surface with a polyanionic solution of carboxymethyl glucomannan (CMGM). The granule has an average diameter of 1.38-1.53 mm and the drug content reaches 62.8%.
The Application & rotundine
1.Tetrahydropalmatine/Rotundine has the protective effect on liver injury induced in mice.
2.Tetrahydropalmatine/Rotundine has analgesia and sedative-hypnotic activity, can depress the chtonic persistent pain and splanchna dull pain.
3.Tetrahydropalmatine/Rotundine has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.
4.Tetrahydropalmatine/Rotundine is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain.
Clinical application
1.It has the effect of promoting blood circulation to remove blood stasis and promoting circulation of gas to relieve pain
2.It is often used for hypochondriac pain due to stagnation of the liver-gas,stomachache due to stagnation of the stomach-gas, hernial pain.
3.Tetrahydropalmatine/Rotundine have analgesia and sedative-hypnotic activity, can depress the chtonic persistent pain and splanchna dull pain. It has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.
4.It is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi,hernial pain. Tetrahydropalmatine has the protective effect on liver injury induced by carbon tetrachloride in mice.
Other Name of rotundine:
Tetrahydropalmatine,AKOS 208-04;L-TETRAHYDROPALMATINE;L-TETRAHYDROPALMATINE HCL;ROTUNDINE;ROTUNDIN HYDRATE;ROTUNDINUM;g)quinolizine,5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-6h-dibenzo(;2,3,9,10-tetramethoxy-berbin
The COA of rotundine
Product Name: rotundine (USP41)
CAS No.:10097-84-4
Batch No.: HNB20220808
Manufacture Date: Aug., 08th, 2022 Analysis Date: Aug., 09th, 2022 Expiry date: Aug.., 07th, 2024
Storage: Well sealed in cool and dry place
Shelf life: 24 Months when properly stored.
ITEMS | SPECIFICATIONS | RESULT |
Appearance | White either type white crystal powder | Complies |
Identification | A,B complies with the standard | Complies |
Residue on ignition | ≤ 0.2% | 0.08% |
Organic impurities | Single impurity:≤ 0.25% | 0.13% |
Total other impurities: ≤ 0.5% | 0.22% | |
Residual solvent | ≤ 0.5% | 0.03% |
Ethanol ≤ 0.5% | 0.02% | |
Loss on drying | ≤ 0.5% | 0.3% |
Chloride | ≤ 0.09% | 0.008% |
Heavy metals | ≤ 10ppm | Complies |
As | ≤ 2ppm | Complies |
Assay(on dried basis) | 98.0%~102.0% | 99.2% |
Conclusion | This product complies with USP41 Standard |