99% Tizanidine Hydrochloride API Pharmaceutical Grade Powder CAS 64461-82-1

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Tizanidine hydrochloride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 64461-82-1 Mf: C9H9Cl2N5S
MW: 290.17 Specification: 99%
Other Name: TIZANIDINE HCL Appearance: White Crystalline Powder
Sample: Available
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Pharmaceutical Tizanidine Hydrochloride Powder


99% Tizanidine Hydrochloride


64461-82-1 API Pharmaceutical

Product Description

64461-82-1 API Pharmaceutical Grade 99% Tizanidine hydrochloride Powder

99% Tizanidine Hydrochloride API Pharmaceutical Grade Powder CAS 64461-82-1 0

Product name

Tizanidine hydrochloride


White Crystalline Powder








Keep in cool dry place.

99% Tizanidine Hydrochloride API Pharmaceutical Grade Powder CAS 64461-82-1 1


The Introductction of Tizanidine hydrochloride


Tizanidine hydrochloride, an imidazoline m-diazepentene derivative with a molecular weight of 290.17, has a structure similar to that of colistin and a melting point of 280°C. The chemical name is 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride, which was developed by Novartis, Switzerland. It is a central skeletal muscle relaxant with an imidazoline structure developed by Novartis, Switzerland.

Tizanidine hydrochloride is used clinically for the treatment of skeletal muscle hypertonia, myospasm and myotonia due to central injury. It is effective in tension headache, trigeminal neuralgia and myofascial pain syndrome. It can also be used as an adjunct to general or regional anesthesia, preoperative and postoperative sedative, and postoperative analgesic.

Tizanidine hydrochloride relieves spasticity without causing muscle weakness, does not produce psychological dependence at therapeutic doses, and is a well-tolerated and efficacious central muscle relaxant.


The Application & Function of Tizanidine hydrochloride


Tizanidine hydrochloride is used for the treatment of skeletal muscle hypertonia, myospasm and myotonia due to traumatic brain and spinal cord injury, cerebral hemorrhage, encephalitis, and multiple sclerosis.


Toxic side effects
When tizanidine hydrochloride tablets are applied at the recommended low dose to relieve painful myospasm, adverse effects are rare and include drowsiness, fatigue, dizziness, dry mouth, nausea, gastrointestinal disturbances, and a mild decrease in blood pressure, usually mild and transient. These adverse reactions, mainly drowsiness, dry mouth, and dizziness, are more common and pronounced when applying the recommended high dose of tizanidine hydrochloride tablets for the treatment of central myasthenia gravis, although they are rarely severe enough to warrant discontinuation of therapy.


Other Name of Tizanidine hydrochloride:  

AB-021;Gibonz;Zanpeak;TERNELIN;SIRDALUD;ZANAFLEX;Enchinin;Astonelin;DS-103-282;TIZANIDINE HCL


The COA of Tizanidine hydrochloride


Product Name Tizanidine hydrochloride Batch No. HNB-220302
Quantity 5000kg Test Sample 10g
Manuf.Date 2022.03.02 Test Date 2022.03.02
Issuing Date 2022.03.02 Expiry Date 2024.03.02
Test parameter Test Iimit Results
Appearance White or slightly yellowish crystalline powder White crystalline Powder
Identification A: IR Conforms
  B: HPLC Conforms
  C: Test of sodium salt Conforms
Assay 99%~101% 99.85%
Appearance of Solution 5% of methanol solution 440nm, ≤0.05% 0.011
Clarity of solution Equal to methanol Pass
pH 7.0~8.5 7.26
Related Substances Any specified impurity: ≤0.2% Not detected
  Any unspecified impurity: ≤0.1% Not detected
  Total impurty:≤0.5% Not detected
Heavy metals ≤10ppm Conforms
Loss on drying ≤0.5%(1g, 100~105℃,3hrs) 0.2%
Conclusion The above material complies with USP 34 standard

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