|Place of Origin:||China|
|Model Number:||Doxepin hydrochloride|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order|
|Einecs No.:||200-077-2||Appearance:||White To Off-white Crystalline Powder|
Doxepin Hydrochloride Antidepressant Powder,
Pharmaceutical Doxepin Hydrochloride,
API Tricyclic Antidepressant
1229-29-4 antidepressant API Pharmaceutical Grade 99% Doxepin hydrochloride Powder
The Introductction of Doxepin hydrochloride
Doxepin is a psychotropic drug that is a tricyclic antidepressant with anxiolytic activity.
Doxepin has antagonistic effects on various receptors, including H1, H2, 5-HT1, 5-HT2, alpha1-adrenergic and mACh.
Doxepin inhibits the reuptake of serotonin and norepinephrine. Its reuptake of dopamine is negligible.
Doxepin hydrochloride is clinically indicated for depression and anxiety neuropathy. It is an antidepressant that inhibits the reuptake of 5-hydroxytryptamine and norepinephrine neurotransmitters in the central nervous system and increases the concentration of these two neurotransmitters in the synaptic gap to exert its antidepressant effect. Of course, doxepin hydrochloride tablets also have sedative effects.
Doxepin hydrochloride tablets may cause drowsiness, tremors, constipation, difficulty in urination, and of course, postural hypotension.
Doxepin hydrochloride is not recommended for patients with severe heart disease, urinary retention, or hepatic impairment.
Doxepin hydrochloride has sedative, hypnotic, antidepressant and anxiolytic effects.
Doxepin hydrochloride is useful for some depressed and anxious patients with sleep disorders.
Doxepin hydrochloride can also be used for the treatment of some allergic diseases.
|Characters||White to off-white crystalline powder||Conform|
|Identification||IR: Should be concordant with the RS spectrum||Conform|
|UV: Should be concordant with the UV spectrum||Conform|
|TLC: The retention time of the main peak of the sample solution should be consistent with that of the control sample||Conform|
|pH||4.5 ~ 6.0||5.0|
|Loss on drying||≤0.5%||0.1%|
|Related substances||Any Impurity ≤0.1%||0.04%|
|Total impurities ≤0.3%||0.05%|
|Assay||99.0% ~ 101.0%||99.8%|
|Conclusion: The above certificate of analysis complies with EP6.0|