| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Bromhexine Hydrochloride |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 611-75-6 | Mf: | C14h21br2cln2 |
|---|---|---|---|
| Specification: | ≥98% | Melting Point: | 240-244 °C |
| Merck: | 14,1391 | MW: | 412.59 |
| EINECS: | 210-280-8 | ||
| High Light: | API Bromhexine Hydrochloride,Chemical Bromhexine HCl Powder,Pharmaceutical Bromhexine Hydrochloride |
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Pharmaceutical Chemical Raw Material Bromhexine Hydrochloride CAS 611-75-6 Bromhexine HCl
| Prodcut name | Bromhexine HCL |
| MOQ | 1KG |
| CAS No. | 611-75-6 |
| Appearance | White Crystalline Powder |
| Molecular Formula | C14H21Br2ClN2 |
| Molecular Weight | 412.59 |
| Assay | 99% |
| Application | Pharma grade |
The Introductction of Bromhexine hydrochloride:
Bromhexine hydrochloride is an organic compound with a molecular formula of C14H21Br2ClN2, a molecular weight of 412.591, a white solid.Bromhexine hydrochloride is usually to treat cute and chronic bronchitis, asthma, bronchiectasis, emphysema, especially suitable for the white sticky sputum cough and the severe acute disease caused by the widespread obstruction of small bronchi caused by sputum.
The Application & Function of Bromhexine hydrochloride:
Bromhexine hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm. This tends to be given to those with respiratory diseases who have difficulty coughing this out otherwise - by breaking it down it becomes smaller and easier to expel and this means they can breathe without their airways being blocked while also providing cough relief. It is preferable to some cough medication as it does not include any sedatives which can otherwise make those using the medication drowsy. At the same time many other cough medicines simply sooth the throat without actually breaking down the phlegm.
Bromhexine hydrochloride has direct effects on the bronchial glands, which promote the release of lysosomes in the mucus secretory cells, causing the dissociation of the sticky sugar fibers in the sputum;It can also inhibit the synthesis of acid glycoprotein in mucous glands and goblet cells, so as to secrete the small molecule glycoprotein with low viscosity, thus reducing the viscosity of sputum and making it easy to cough.In addition, it can stimulate the gastric mucosa reflex to increase the secretion of the respiratory glands and dilute sputum.
The COA of Bromhexine hydrochloride :
| ITEMS | STANDARD | RESULTS | |
| Appearance | White or almost white crystalline powder | almost white crystalline powder | |
solubility |
Very slightly soluble in water ,slightly soluble in alcohol and in methylenechloride | Complies | |
| Identification | IR | Complies | |
| TLC | Complies | ||
| Brownish-yellow colour develops in the lower layer | Complies | ||
| The reaction of primary aromatic amines | Complies | ||
| Reaction of chlorides | Complies | ||
| Appearance of solution | The solution is clear and not more intensely coloured than reference solution Y6 | Complies | |
| Related substances | Total impurity | <=0. 3 | 0. 3 |
| any impurity | <=0. 2 | 0. 1 | |
| any impurity>0.1% not more than i peak an 1 peak |
Complies | ||
Loss on drying |
<=1.0 | 0. 2 | |
| Sulphated ash | <=0. 1 | 0. 08 | |
| Assay | 98. 5 ~101. 5 | 99. 6 | |