Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | Xylazine Hydrochloride |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 23076-35-9 | Mf: | C12H17ClN2S |
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MW: | 256.8 | Specification: | 99% |
Grade: | Medicine Grade | Appearance: | White Crystalline Powder |
Sample: | Available | ||
High Light: | Raw Xylazine Hydrochloride Powder,API Xylazine Hydrochloride,Medicine Grade Xylazine Hydrochloride |
23076-35-9 Veterinary API 99% Xylazine Hydrochloride Raw Crystalline Powder
Product name |
Xylazine Hydrochloride |
Appearance |
White crystalline powder |
CAS |
23076-35-9 |
MF |
C12H17ClN2S |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of Xylazine Hydrochloride
Xylazine HCl is an alpha2-adrenergic receptor agonist used as a tranquilizer and muscle relaxant.
Xylazine Hydrochloride is a sedative veterinary drug. It can cause mild inhibition of the central nervous system, weakening the functional activities, so as to eliminate restlessness and restoration of quiet class of drugs. In recent years, individual livestock breeders driven by economic interests, unauthorized in the process of raising livestock and poultry to add such drugs to play a sedative hypnotic, weight gain and fattening, shorten the role of slaughter time; in addition, in the process of animal transportation, in order to reduce animal death and weight loss, to prevent the reduction of meat quality, also often use such drugs to reduce the loss of stress.
Xylazine Hydrochloride in vivo study
Xylazine (5.2 mg/kg; intraperitoneal injection; for 10-60 minutes; male Sprague-Dawley rats) administration alters mRNA expression and protein phosphorylation levels of AMPK signaling molecules, suggesting that the LKB1-AMPK pathway plays a role in the sedative and tranquilizing effects in the CNS caused by Xylazine treatment.
Animal Model: | Male Sprague-Dawley rats (160-180 g)[ |
Dosage: | 5.2 mg/kg |
Administration: | Intraperitoneal injection; for 10 minutes, 20 minutes, 40 minutes or 60 minutes |
Result: | Increased in AMPK activity in the cerebral cortex, hippocampus, thalamus and cerebellum. Phosphorylated LKB1 and AMPKα protein levels were decreased. |
Adverse reactions and side effects
Xylazine Hydrochloride is used as an alpha2-adrenoceptor agonist, sedative and muscle relaxant.
Other Name of Xylazine Hydrochloride:
2-[2,6-DIMETHYLPHENYLAMINO]-4H-5,6-DIHYDROTHIAZINEHYDROCHLORIDE;
2-[(2,6-DIMETHYLPHENYL)AMINO]-5,6-DIHYDRO-4H-1,3-THIAZINEHYDROCHLORIDE;
2-(2,6-DIMETHYLPHENYLAMINO)-5,6-DIHYDRO-4H-THIAZINEHYDROCHLORIDE;XYLAZINEHYDROCHLORIDEVETRANAL,100MG;
XYLAZINEHYDROCHLORIDE,USPSTANDARD;XYLAZINEHYDROCHLORIDE,EPSTANDARD;
XYLAZINEHYDROCHLORIDE,MM(CRMSTANDARD);XYLAZINEHYDROCHLORIDE,IMP.A(EP):2,6-DIMETHYLANILINEMM(CRMSTANDARD)
The COA of Xylazine Hydrochloride
Batch Number: HNB2020106
Batch Quantity: 120kg |
Manufacture Date: May.06,2022 Analysis Date: May.07,202 |
Storage:Store in cool & dry place. Store in well-closed containers. |
Shelf life:2 years when properly stored. |
ITEMS OF ANALYSIS |
SPECIFICATIONS |
RESULT |
Assay(Dry base by HPLC) | 98%~102% | 99.82% |
Appearance | White or almost white crystalline powder | Complies |
Identification | A: IR absorption | Complies |
B: the Thin-layer chromatographic identification test | Complies | |
Melting range | 164℃~168℃ | 164.5℃~166.4℃ |
pH | 4.0~6.0 | 5.09 |
Residue on Ignition | ≤0.1% | 0.08% |
Loss on drying | ≤1.0% | 0.12% |
Total Heavy Metals | ≤20ppm | Complies |
Chromatographic purity | Total impurities≤2.0% | Complies |
Conclusion | Conforms with the Standard |