Autumnale Extract 98% Colchicine Powder CAS 64-86-8
The Introductction of Colchicine:
Colchicine is one of a group of macrocyclic alkaloids. Chemical formula: C22H23NO6. It is commonly found in the liliaceae plants of Jialan and Lijiangshan, with the content of 0.11% and 0.1%, respectively. Alkaloids, extracted from the plant colchicine, inhibit the formation of spindle filaments and thus delay the division of the centromere..
The Application & Function of Colchicine:
Function of colchicine
1. It is anti-gout, anti-tumor, inhibiting the mitotic cell stopping in M phase.
2.It has the significant effects on breast cancer, cervical cancer, esophageal cancer, lung cancer,gastric cancer and chronic myelogenous leukemia.
3.It also can be used for acute gout, anti-inflammatory analgesic.
4.In recent years ,furtherly expand its clinical application, for example:to prevent atherosclerosis damage;to cure the liver cirrhosis; to relief the cycle heat caused by abnormal catecholamine, the Behcet's disease; the lumbar disc herniation,intractable waist pain and sciatica; prevent intestine adhesion.
5.In addition, its used as the treatment of Purple epilepsy caused thrombocytopenia; Persistent apophysis erythema;Advanced schistosomiasis;
6.Moreover, using colchicine three can get the polyploidy,so Colchicine is indispensable in chromosome research...
Application of colchicine
Colchicine is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (Autumn crocus, Colchicum autumnale, also known as the "Meadow saffron"). Originally used to treat rheumatic complaints and especially gout, it was also prescribed for its cathartic and emetic effects. Its present medicinal use is mainly in the treatment of gout; as well, it is being investigated for its potential use as an anti-cancer drug. It can also be used as initial treatment for pericarditis and preventing recurrences of the condition. In neurons, axoplasmic transport is disrupted by colchicine. .
It has anti-anxiety effect and few adverse reactions. Regulates the autonomic nervous system. In particular, the drug not only has an antagonistic effect on abnormal behavior caused by anxiety, but also has an effect on abnormal physiological and biochemical phenomena. Suitable for various physical and mental disorders caused by anxiety disorders
The COA of Colchicine :
||Light Yellow powder, neutral odor, highly hygroscopic
||Standard solution and test solution same spot,RF
|Heavy metals (as PB)
|Phosphate Ion (P)
||Spot not bigger than standard solution spot
|Assay (dried basis)
|Assay (dried basis)
Hot sale production: