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HPLC Antipyretic Analgesic 99% Paracetamol API Powder CAS 103-90-2

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Paracetamol powder
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 103-90-2 Mf: C8H9NO2
MW: 151.16 Specification: ≥98%
Einecs No.: 203-157-5 Appearance: White Crystalline Powder
Whatsapp: +86152 029 61574
High Light:

99% HPLC Paracetamol API Powder

,

API Paracetamol Powder Antipyretic


Product Description

Paracetamol API Powder Antipyretic Analgesics Powder CAS 103-90-2 Paracetamol 99%

 

Product Name

Paracetamol/Acetaminophen

Appearance

White or white crystalline powder

Assay

99%min

Test

HPLC

Certificate

ISO 9001

CAS

103-90-2

MF

C17H19N3O3S

Einecs No

137-58-6

Dosage Form

Powder

Storage Temperature

Keep in a cool, dry, dark location in a tightly sealed container or cylinder.

Shelf Life

24 Months

 

The Introductction of Paracetamol:

 

HPLC  Antipyretic Analgesic 99% Paracetamol API Powder CAS 103-90-2 0

             The antipyretic and analgesic acetaminophen, this product is a metabolite of phenacetin, regulates central prostaglandin synthase by inhibiting hypothalamic body temperature. Reduce the synthesis and release of prostaglandin PGE1, bradykinin and histamine. PGE1 mainly acts on the nerve center. Its decrease will lead to a decrease in the central body temperature setting point, and the body surface temperature sensor will feel relatively hot, and then through nerve regulation, it will cause peripheral blood vessels to dilate and sweat to achieve antipyretic effect, which inhibits the central nervous system.

              The effect of prostaglandin synthesis is similar to that of aspirin, but its anti-inflammatory effect is weak. No effect on platelets and coagulation mechanism.

             Indications: Used for cold and fever, joint pain, neuralgia, migraine, cancer pain and postoperative pain relief. This product can also be used for patients who are allergic to aspirin, intolerant or not suitable for aspirin (chickenpox, hemophilia and other bleeding disorders, etc.).
 

 

Function of Paracetamol


Paracetamol is a commonly used antipyretic analgesic. Its main component is acetaminophen. Therefore, paracetamol can achieve the purpose of heat dissipation by inhibiting the activity of cyclooxygenase and the synthesis of prostaglandin. At the same time, it can have the effect of analgesia. Clinically, paracetamol is usually used to treat fever, headache and neuralgia caused by a cold.

 

1. Antipyretic
Paracetamol is the main component of paracetamol, which will significantly inhibit the synthesis of cyclooxygenase and prostaglandin in the human body after entering the human body. From the trade name of the drug, it can also be seen that paracetamol has a good therapeutic effect of heat dissipation and antipyretic, which is also one of its main effects. By inhibiting the activity of cyclooxygenase and the synthesis of prostaglandins, we can adjust the control center of hypothalamus and regulate body temperature, so as to have the effect of cooling and antipyretic.

 

2. Analgesia
Analgesic effect is the second largest effect of paracetamol, but the analgesic effect will be weaker than the antipyretic effect. Acetaminophen, as a non steroidal compound, can inhibit the synthesis and release of prostaglandins, so it can alleviate many types of pain, such as headache, migraine, toothache or some neuralgia, muscle pain, joint pain caused by cold, etc.

 

The Application of Paracetamol:


1. Paracetamol is the most commonly used non-anti-inflammatory antipyretic analgesics, antipyretic effect similar analgesic effect is weak, no anti-inflammatory anti-rheumatic effects, acetanilide drugs is the best varieties. Particularly suitable for patients who can not use carboxylic acids. For cold, toothache embolism. Acetaminophen is also an intermediate for organic synthesis, hydrogen peroxide stabilizer, and photographic chemicals.
2. Paracetamol for antipyretic, analgesic, anti-rheumatic drugs
3. Paracetamol for organic synthesis intermediates, hydrogen peroxide stabilizer, photographic chemicals, non-anti-inflammatory antipyretic analgesics.


The COA of ​Paracetamol:

 

ITEM

SPECIFICATION

RESULT

Appearance

White, crystalline powder or colorless crystals

Conforms

Identification

Accord With BP2007

Conforms

Assay

98.5%~101.0%

99.97%

Melting point

75°C~78°C

77°C

Optical rotation

-0.05°~+0.05°

0.00°

Heavy metals

≤ 0.001%

<0.001%

Related substances

Impurity B

≤ 0.3%

Conforms

Any other impurity

≤ 0.3%

Conforms

Total of all impurities apart from impurity B

≤ 0.7%

Passes

Impurity F

≤ 0.1%

Not detected

Sulphated ash

≤ 0.1%

0.02%

Appearance of solution

Accord With BP2007

Conforms

Contact Details
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Phone Number : +8618292978289

WhatsApp : +8618629242069