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99% API Pharmaceutical Fluoxetine Hydrochloride Powder For Human Antidepressant

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Fluoxetine Hydrochloride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 59333-67-4 Mf: C17H19ClF3NO
MW: 345.79 Specification: 99%
EINECS No.: 260-101-2 Appearance: White To Off-white Powder
Sample: Available
High Light:

Antidepressant API Powder

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99% Fluoxetine Hydrochloride Powder

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Pharmaceutical Fluoxetine Hydrochloride Powder


Product Description

59333-67-4 Human antidepressant API 99% Fluoxetine Hydrochloride powder

99% API Pharmaceutical Fluoxetine Hydrochloride Powder For Human Antidepressant 0

Product name

Fluoxetine Hydrochloride

Appearance

White to off-white powder

CAS

59333-67-4

MF

C17H19ClF3NO

Purity

99%

Storage

Keep in cool dry place.

99% API Pharmaceutical Fluoxetine Hydrochloride Powder For Human Antidepressant 1

 

The Introductction of Fluoxetine Hydrochloride

 

Fluoxetine hydrochloride is the world's first marketed antidepressant drug as a selective 5-hydroxytryptamine reuptake inhibitor (SSRIs), primarily inhibiting central nervous reuptake of 5-hydroxytryptamine for the treatment of depression and its concomitant anxiety, and for the treatment of obsessive-compulsive disorder and bulimia nervosa (bulimia nervosa).


Fluoxetine blocks 5-HT2A receptors and restores DA and NE levels by inhibiting 5-HT2A receptors. Also, fluoxetine unblocks the inhibitory effect of gamma-aminobutyric acid (GABA) neurons on NE and DA release via 5-HT2C receptors. In addition to increasing the 5-HT concentration in the synaptic gap, it is the direct and indirect restoration of DA and NE levels based on the action of fluoxetine on 5-HT2A and 5-HT2C that has NE and DA derepression properties (NDDI).


Fluoxetine hydrochloride can be used for all types of depression, especially for depressive symptoms associated with organic diseases and depression in old age. It is also used to treat post-schizophrenic depression. It is also used for obsessive-compulsive disorder, phobias, anxiety symptoms of depression, bulimia nervosa, weight loss, and as an adjunct to smoking cessation.

 

Adverse effects of Fluoxetine Hydrochloride.

The main adverse reactions of fluoxetine hydrochloride are nausea, hypersensitivity and insomnia, which disappear on their own after stopping the drug.

Other side effects include headache, anxiety, excessive sweating, diarrhea, blurred vision, dry mouth, sexual dysfunction, etc.

 

The Application & Function of Fluoxetine Hydrochloride

 

Fluoxetine hydrochloride is indicated for the treatment of various depressive psychiatric disorders, including mild or major depression, depression in bipolar disorder, psychogenic depression and depressive neurosis. The mechanism of action is to inhibit neuronal uptake of 5-hydroxytryptamine from the synaptic gap and to increase the actual availability of this neurotransmitter in the gap, thereby improving the affective state and treating depressive psychiatric disorders.

 

Other Name of Fluoxetine Hydrochloride:

 

Fluoxetine HCL; Fluoxetinhydrochloride; Fluoxetin HCL;

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride (1:1);

6,11-dihydroxy-3,3-dimethyl-5-(3-methylbut-2-en-1-yl)-3,12-dihydro-7H-pyrano[2,3-c]acridin-7-one

 

The COA of Fluoxetine Hydrochloride

 

Product Name: Fluoxetine Hydrochloride

Batch No.: HNB220425

Batch Quantity: 100kg

Manu. Date: Apr., 25th, 2022 Analysis Date: Apr., 26th, 2022 Expiry date:Apr., 24th, 2024

Storage: Store in cool&dry place, in well-closed containers. Shelf life: 24 Months when properly stored.

 

TEST ITEMS SPECIFICATIONS RESULT
Appearance White to off-white powder Complies
Assay 98.5%-100.5% 99.5%
Identification The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation,as obtained in the assay Complies
Water ≤ 0.5% 0.12%
Residue on ignition ≤ 0.2% 0.11%
Heavy metals ≤ 0.001% Complies
Related compounds by hplc Fructose ≤ 0.3% 0.03%
  Compound A ≤ 0.3% 0.04%
  Other individual impurity ≤ 0.1% 0.01%
  Total impurities not more than 0.5% 0.08
Particle size 90% less than 350 microns Complies
Limit of sulfamate and sulfate

Sulfamate ion not more than 0.10%

Sulfate ion not more than 0.10%

Complies
Conclusion Conform with the USP Standard

Contact Details
Beryl Jia

Phone Number : +8618092068319

WhatsApp : +8618629242069