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Human Antiepileptics API Pharmaceutical Neurontin 99% Gabapentin Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Gabapentin
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 60142-96-3 Mf: C9H17NO2
MW: 171.24 Specification: 99%
Grade: Medicine Grade Appearance: White To Off-white Crystalline Powder
Sample: Available
High Light:

API Antiepileptics Gabapentin Powder

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99% Human Neurontin Powder

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Pharmaceutical Gabapentin Powder


Product Description

60142-96-3 Human Antiepileptics API Neurontin 99% Gabapentin powder

Human Antiepileptics API Pharmaceutical Neurontin 99% Gabapentin Powder 0

Product name

Gabapentin

Appearance

White to off-white powder

CAS

60142-96-3

MF

C9H17NO2

Purity

99%

Storage

Keep in cool dry place.

Human Antiepileptics API Pharmaceutical Neurontin 99% Gabapentin Powder 1

 

The Introductction of Gabapentin

 

Gabapentin is a novel antiepileptic drug that is a derivative of gamma-aminobutyric acid (GABA) with pharmacological effects different from those of existing antiepileptic drugs. Recent studies have shown that the effect of gabapentin is to alter GABA metabolism. Gabapentin has been shown to prevent epilepsy in various animal models, in addition to showing effects in animal models of spasticity, analgesia, and amyotrophic sclerosis. Gabapentin has a high affinity for novel binding sites in brain tissue, it crosses a number of barriers in vivo via amino acid transfer bodies, and it has fewer behavioral and cardiovascular side effects compared to other anticonvulsants.


Gabapentin is structurally similar to γ-aminobutyric acid (GABA), but is not an agonist of GABA receptors, and the receptors bound to neurons in brain tissue have not been identified, so its mechanism of action is not yet understood. Studies have shown that when gabapentin is added to treatment, there is a significant reduction in seizure frequency, satisfactory long-term outcome, and fewer adverse effects. After seizure control, if gabapentin is used alone, it is effective in only some patients. It is not effective for loss-of-nerve seizures.

 

Adverse effects of Gabapentin.


1. Drowsiness, vertigo, dyskinesia, fatigue, nystagmus, headache, tremor, diplopia, rhinitis, and nausea and vomiting are common. These reactions are usually reduced with continued use of the drug.
2. Occasional convulsions, pharyngitis, dysphonia, weight gain, dyspepsia, amnesia, hypersensitivity, etc.
3. Rarely pancreatitis, impaired liver function and S-Jo syndrome

 

The Application & Function of Gabapentin

 

1. Gabapentin is used to control partial seizures.


2. Gabapentin is used in refractory incomplete epilepsy. The combination of the anxiolytic gabapentin and the antiviral valacyclovir has been reported to reduce the risk of post-acute herpes zoster neuralgia.

 

Other Name of Gabapentin:

 

NEURONTIN;GABAPENTINE;GABAPENTIN HYDROCHLORIDE;

GABAPENTIN;GOE-3450;

(1-AMINOMETHYL-CYCLOHEXYL)-ACETIC ACID;

1-(AMINOMETHYL)CYCLOHEXANEACETIC ACID;

AKOS 92109

 

The COA of Gabapentin

 

Product Name: Gabapentin

Batch No.: HNB220420

Batch Quantity: 200kg

Manu. Date: Apr., 20th, 2022 Analysis Date: Apr., 21th, 2022 Expiry date:Apr., 19th, 2024

Storage: Store in cool&dry place, in well-closed containers. Shelf life: 24 Months when properly stored.

 

TEST ITEMS SPECIFICATIONS RESULT
Appearance White to off-white crystalline powder Complies
Assay 98.0%-102.0% 99.2%
Identification The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation,as obtained in the assay Complies
Specific rotation Between -28.6°and -35.0°, measured at 20° -32.8°
Water ≤ 0.5% 0.12%
Residue on ignition ≤ 0.2% 0.11%
Heavy metals ≤ 0.001% Complies
Related compounds by hplc Fructose ≤ 0.3% 0.03%
  Compound A ≤ 0.3% 0.04%
  Other individual impurity ≤ 0.1% 0.01%
  Total impurities not more than 0.5% 0.08
Particle size 90% less than 350 microns Complies
Limit of sulfamate and sulfate

Sulfamate ion not more than 0.10%

Sulfate ion not more than 0.10%

Complies
Residual Solvent Methylene Chloride not more than 250μg/g Not detected
  Acetone not mor than 2500μg/g Not detected
  Isopropanol not more than 5000μg/g Not detected
  Ethanenitrile not more than 400μg/g Not detected
  n-hexane not more than 290μg/g Not detected
  Ethyl Acetate not more than 2500μg/g Not detected
  Pyridine not more than 100μg/g Not detected
Conclusion Conform with the USP Standard

Contact Details
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Phone Number : +8618092068319

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