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CAS 138786-67-1 Gastrointestinal Agents Pantoprazole Sodium Pharmaceutical Raw Materials

Basic Information
Place of Origin: China
Brand Name: BCB
Certification: ISO
Model Number: Pantoprazole Sodium
Minimum Order Quantity: 1
Price: 350
Packaging Details: 1kg/bag, 25kg/drum
Delivery Time: 7 working days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 10000kg/month
Detail Information
Purity: 99% Mf: C16H15F2N3O4S
Cas No.: 138786-67-1 Einecs No.: /
Appearance: White To Off White Crystalline Powder Usage: Pharmaceutical Intermediates
Shelf Life: 24 Month Molecular Weight: 405.352
Test Method: HPLC Density: 1.49-1.51
Melting Point: 199-202 ° C Boiling Point: 586.9°C
PKA: 9.56±0.10(Predicted)
High Light:

Gastrointestinal Agents Pantoprazole Sodium

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Pharmaceutical Raw Pantoprazole Sodium

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Pantoprazole Sodium Gastric Prokinetic Agent


Product Description

Pharmaceutical Raw Materials Gastrointestinal Agents Pantoprazole Sodium CAS 138786-67-1

 

Prodcut name

Pantoprazole Sodium

MOQ 1KG
CAS No. 138786-67-1
Appearance White to off white crystalline powder
Molecular Formula C16H14F2N3NaO4S
Molecular Weight 405.35
Assay 99%
Application Pharma grade

 

 

The Introductction of Pantoprazole Sodium:

 

Pantoprazole sodium, racemicsodium5-(difluoromethoxy)-2-[[3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sesquihydrate is a white tooff-white crystalline powder that is freely soluble in water,very slightly soluble in phosphate buffer at pH 7.4, and practicallyinsoluble in n-hexanie. The benzimidazole of this drughas a weakly basic nitrogen (pyridinie N, pKa 3.83) and an benzimidazoleproton (pKa 0.11), facilitating formulation as asodium salt. The stability of the compound in aqueous solutionis pH dependent; the rate of degradation increases with decreasingpH. At ambient temperature, the degradation half-lifeis approximately 2.8 hours at pH 5.0 and approximately 220hours at pH 7.8.

 

 

The Application & Function of Pantoprazole Sodium:

 

Pantoprazole Sodium Sesquihydrate is a medicie which is used in gastro-oesophageal reflux disease, prevention of duodenal ulcers linked to NSAID therapy in patients at risk, prevention of the relapse of oesophagitis.

 

The COA of Pantoprazole Sodium:

 

Item Standard Result
Appearance White to off white crystalline powder Complies
  I.R similar to standard Complies
Identification The retention time of the major peak corresponds to standard Complies
  Masculine Reaciton for Sodium Complies
Water 5.0% - 8.0% 5.90%
Heavy metals Not more than 0.002% Complies
  Impurity A ≤ 0.20% 0.08%
  Impurity B ≤0.15% Less than detectable limit
  Impurity C 0.10% Less than detectable limit
Related compounds

Impurity D & F ≤0.20%

Less than detectable limit
  Impurity E 0.10% 0.03%
  Any other individual imp 0.10% 0.07%
  Total impurities ≤0.50% 0.18%
Residual solvent Ethyl acetate 0.50% 0.20%
Assay 98.0% - 102.0% 99.9%
Conclusion Up to the Standard .  

 

Related product:

 

Product Name CAS No.

Pranlukast

103177-37-3
Pantoprazole 102625-70-7
Docusate sodium 577-11-7

 

 

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