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CAS 124-20-9 Amino Acid Powder Spermidine Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Spermidine
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 124-20-9 Mf: C7H19N3
MW: 145.25 Specification: ≥98%
Appearance: White Crystalline Powder Product Name: Spermidine Powder
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CAS 124-20-9 Amino Acid Powder

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Biological Processes Spermidine Amino Acid Powder

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Biological spermidine powder cas 124-20-9


Product Description

CAS 124-20-9 Amino Acid Powder Spermidine Powder

结构式

Product Name Spermidine
CAS NO. 124-20-9
MF C7H19N3
MW 145.25
EINECS 204-689-0

Whatsapp: +86 152 029 61574

 

The Spermidine Introductction

 

Spermidine, a natural substance, may prevent age-related memory decline, which is the result of a cooperative study by scientists in Germany and Austria. On September 1, 2013, the results were published in the online edition of nature neuroscience. [1]

The results of a team study by Professor Stephen sigerist of the Free University of Berlin in Germany and Professor Frank madeO of Carl franzens University in Austria show that spermidine can return the brain performance of old fruit flies to the level of their youth. In biology, the memory process of flies and mice is similar to that of humans at the molecular level. Therefore, scientists believe that the research will help to develop drugs to delay the onset of Alzheimer's disease.

Biologists have been able to prove that the endogenous substance spermidine can trigger autophagy. In October 2009, Professor madeO published the related paper "spermidine induced autophagy promotes longevity" in nature · cell biology. Further research by the joint research team showed that by feeding fruit flies with spermidine, the amount of protein condensation in their brains decreased significantly, and the memory ability of fruit flies increased. This result is verified by measurement, because fruit flies learn through the classical Pavlovian conditioned reflex, remember what they have learned, and adjust their later behavior accordingly. [1]

The scientists say that research applied to patients is the next goal of the joint research group. Human memory begins to weaken after the age of 50. This attenuation accelerates with age. Due to the increase of life expectancy, dementia induced by age factors increased significantly. Spermidine concentrations in Drosophila and humans also decreased with age. If spermidine supplementation can delay the onset of dementia, it means an important breakthrough for patients and society. [1]

Delay protein aging

Spermidine has different effects on proteins with different molecular weights. Some high molecular weight bands increase significantly with the extension of spermidine treatment time, indicating that there may be protein synthesis, but this part of the protein accounts for a small percentage of the total protein, and has no obvious effect on medium and small molecular weight proteins, It is speculated that the degradation of these proteins may play a key role in the aging process. Once 72 hours, these proteins may play a key role in the aging process, Controlling the degradation of these proteins can delay the process of aging. The reason why spermidine can delay its aging may be to promote the synthesis of these proteins or prevent their degradation.

 

Spermidine is a low-molecular-weight aliphatic carbide containing 3 amine groups, and is one of the natural polyamines present
in all organisms. It is an important raw material for pharmaceutical synthesis and is widely used in the synthesis of  pharmaceutical intermediates.

 

The Spermidine Application & Function

Spermidine participates in many biological processes in the organism, such as regulating cell proliferation, cell senescence,
organ development, immunity and cancer and other physiological and pathological processes. Recent studies have shown that spermidine plays an important role in regulating processes such as synaptic plasticity, oxidative stress and autophagy in the nervous system.

 

The Spermidine COA

 

Item Specification Results
APPEARANCE WHITE CONFORMS
SOLUBILITY FREELY SOLUBLE IN CHLOROFORM;SOLUBLE IN WATER OR METHANOL;INSOLUBLE IN ETHER CONFORMS
PH 5.0-7.2 6.4
LOSS ON DRYING ≤4.5% 2.9%
RESIDUEON IGNITION ≤2.5% 0.2%
HEAVY METALS ≤20PPM <20PPM
TYRAMINE ≤0.35% 0.04%
RELATED COMPOSITIONS TYLOSIN A ≥80% A+B+C+D ≥95% 92% 97%
Conclusion Confirm with the standard  

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