Place of Origin: | China |
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Brand Name: | HNB |
Certification: | ISO |
Model Number: | Aminophylline |
Minimum Order Quantity: | 1KG |
Price: | Negotiable |
Packaging Details: | Aluminum foil bag |
Delivery Time: | Usually3-5days |
Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram,Alibaba Assurance Order |
Supply Ability: | 5000kg/Month |
CAS: | 317-34-0 | Mf: | C16H24N10O4 |
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MW: | 420.43 | Specification: | 99% |
Einecs No.: | 206-264-5 | Appearance: | White To Yellowish Powder |
Sample: | Available | ||
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317-34-0 HUMAN API ANTIASTHMATIC RAW MATERIAL POWDER 99% AMINOPHYLLINE
Product name |
AMINOPHYLLINE |
Appearance |
White to Yellowish Powder |
CAS |
317-34-0 |
MF |
C16H24N10O4 |
Purity |
99% |
Storage |
Keep in cool dry place. |
The Introductction of AMINOPHYLLINE
Aminophylline is a compound salt of theophylline and ethylenediamine. Its pharmacological effect mainly comes from theophylline, and its water solubility is enhanced by ethylenediamine. It is insoluble in methanol, ethanol and ethe*, and has a direct relaxing effect on the smooth muscle of the respiratory tract.
Aminophylline relaxes bronchial smooth muscle, and also relaxes various smooth muscles of the intestine and biliary tract, and has a relieving effect on congestion and edema of bronchial mucosa. Aminophylline increases cardiac output, dilates the output and input renal small arteries, increases glomerular filtration rate and renal blood flow, and inhibits the reabsorption of sodium and chloride ions from the distal renal tubules.
Aminophylline increases contractility of isolated skeletal muscle; improves muscle contractility in the setting of chronic obstructive pulmonary disease. Theophylline increases ventilatory insufficiency during hypoxia is thought to be the result of its increased contraction of the diaphragm, and its action in this regard exceeds that of the respiratory center.
The Application & Function of AMINOPHYLLINE
Other Name of AMINOPHYLLINE: 1,3-Dimethyl-3,7-dihydro-1H-purin-2,6-dion-ethan-1,2-diamin(2:1); Theophylline ethylenediamine; Aminophylline; Ethylenediamine compd. with Theophylline (1:2); Aminophylline ethylenediamine
The COA of AMINOPHYLLINE
ITEMS OF ANALYSIS | SPECIFICATION | RESULT |
Characteristics | White or yellowish powder, granular | White powder |
Identification | IR: The infrared absorption spectrum should be concordant with the reference spectrum | Complies |
Chemical Reaction: Positive reaction | Complies | |
HPLC: The retention time of the principal peak in the substance being examined is identical with reference solution | Complies | |
Clarify and color of solution | The solution is clear and colorless. Any colour producted is not more intense than that of reference solution YG2 | Complies |
Residue on ignition | ≤0.1% | 0.06% |
Related substances | ≤0.5% | 0.13% |
Residual solvent | Meets the requirments | Complies |
Water | ≤1.5% | 0.65% |
Total Plate Count | ≤1000cfu/g | 30cfu/g |
Yeast & Mold | ≤100cfu/g | 15cfu/g |
E.Coli | Negative | Complies |
S.Aureus | Negative | Complies |
Salmonella | Negative | Complies |
Assay | Ethylene diamine: 13.5-15.0% | 14.7% |
Anhydrous Theophylline: 84.0-87.4% | 84.4% | |
Conclusion | Confirm with the standard |