products

73590-58-6 Mopral Omeprazole Gastrointestinal Api Medicine 99%

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: OMEPRAZOLE
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 73590-58-6 Mf: C17H19N3O3S
MW: 345.42 Specification: 99%
Einecs No.: 201-212-8 Appearance: White Or Off-white Crystalline Powder
Sample: Available
High Light:

73590-58-6 Mopral Omeprazole

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Mopral Omeprazole Gastrointestinal Api 99%

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73590-58-6 active pharmaceutical ingredient raw material


Product Description

73590-58-6 HUMAN API GASTROINTESTINAL MEDICINE RAW MATERIAL POWDER 99% MOPRAL OMEPRAZOLE

73590-58-6 Mopral Omeprazole Gastrointestinal Api Medicine 99% 0

Product name

MOPRAL; OMEPRAZOLE

Appearance

White or Off-white Crystalline Powder

CAS

73590-58-6

MF

C17H19N3O3S

Purity

99%

Storage

Keep in cool dry place.

73590-58-6 Mopral Omeprazole Gastrointestinal Api Medicine 99% 1

 

The Introductction of OMEPRAZOLE

 

Omeprazole is a proton pump inhibitor used for the treatment of peptic ulcer and gastroesophageal reflux disease (GERD). It specifically acts on the site of the proton pump in the gastric wall cell and is converted into the active form of sulfenamide, which then irreversibly binds to the sulfhydryl group of the proton pump through the disulfide bond to produce a complex of sulfenamide and the proton pump (H+-K+-ATPase), thereby inhibiting the activity of the enzyme and preventing the transport of H+ from the wall cell into the gastric lumen, blocking the last step of gastric acid secretion, which can greatly reduce the amount of gastric acid in the gastric juice.


Omeprazole has a strong and long-lasting inhibitory effect on gastric acid secretion caused by a variety of causes (e.g., basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin and stimulation of the vagus nerve, including gastric acid secretion caused by dibutyl cyclic adenosine acid that cannot be inhibited by H2 receptor blocking drugs).


Omeprazole is used clinically to treat peptic ulcer, reflux esophagitis, Zollinger-Ellison syndrome, and eradication of Helicobacter pylori (HP) with satisfactory results.


However, it should be noted that excessive use of acid-suppressing drugs such as omeprazole can lead to a decrease in the concentration of gastric acid and weakened acidity, then the germs that enter the stomach may not be killed and enter the intestine, doubling the risk of intestinal infection with germs, then diarrhea is possible. Because of the lowered stomach acid affects digestion, which in turn affects the intestinal absorption of calcium, iron and other trace elements and vitamins, leading to calcium deficiency in the body and susceptibility to fractures.

 

The Application & Function of OMEPRAZOLE

 

1. Omeprazole is used for gastric and duodenal ulcers, stress ulcers, etc.

2. Omeprazole is used for reflux esophagitis and gastrinoma.

3. Omeprazole injection can also be used for.
   ① Gastrointestinal bleeding, such as peptic ulcer bleeding, anastomotic ulcer bleeding, etc., and prevention of upper gastrointestinal bleeding caused by serious diseases (such as cerebral hemorrhage, severe trauma, etc.) and after gastric surgery.
   ② Acute gastric mucosal injury that is complicated during stressful conditions or caused by NSAIDs.
   ③ Patients under general anesthesia or after major surgery and coma to prevent gastric acid reflux and aspiration pneumonia.

4. Omeprazole with amoxicillin and clarithromycin, or in combination with metronidazole and clarithromycin, can effectively kill Helicobacter pylori (Hp).

 

Other Name of OMEPRAZOLE: LOSEC; MEPRAL; GASTROGARD; OMEPRAZOLE; Loec; Moprial; Omeprazolum; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole

 

 

The COA of OMEPRAZOLE

 

Product OMEPRAZOLE Batch No 20190410
Date of Manufacture 2021-04-10 Quantity 1000kg
Date of Certificate 2021-04-29 CAS No. 73590-58-6
Date of Expire 2023-04-09 Sample 10g
Storage Store in cool & dry place, in well-closed containers.
Test Items Specification Results
Appearance White or almost white crystalline powder White crystalline powder
Identification

Infrared absorption:

Must similar to reference standard

Conforms
 

Ultraviolet absorption:

Must similar to reference standard

Conforms
  Test for potassium: Must be positive Conforms
Water ≦ 0.5% 0.1%
Loss on drying ≦ 0.5% 0.2%
Residue on Ignition ≦ 0.2% 0.05%
Chromatographic purity Any individual impurity ≦ 0.2% 0.01%
Total impurities ≦ 0.5% 0.04%
Heavy metals ≦ 10 ppm Conforms
Residual solvents Cyclohexane ≦ 0.1% 0.007%
Isopropyl alcohol ≦ 0.2% 0.03%
Assay 98.5%~101.0% 99.5%
Conclusion Complies with USP30 standards.

Contact Details
Beryl Jia

Phone Number : +8618092068319

WhatsApp : +8618629242069