| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | OMEPRAZOLE |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually3-5days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram，Alibaba Assurance Order |
| Supply Ability: | 5000kg/Month |
| CAS: | 73590-58-6 | Mf: | C17H19N3O3S |
|---|---|---|---|
| MW: | 345.42 | Specification: | 99% |
| Einecs No.: | 201-212-8 | Appearance: | White Or Off-white Crystalline Powder |
| Sample: | Available | ||
| High Light: | 73590-58-6 Mopral Omeprazole,Mopral Omeprazole Gastrointestinal Api 99%,73590-58-6 active pharmaceutical ingredient raw material |
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73590-58-6 HUMAN API GASTROINTESTINAL MEDICINE RAW MATERIAL POWDER 99% MOPRAL OMEPRAZOLE
|
Product name |
MOPRAL; OMEPRAZOLE |
|
Appearance |
White or Off-white Crystalline Powder |
|
CAS |
73590-58-6 |
|
MF |
C17H19N3O3S |
|
Purity |
99% |
|
Storage |
Keep in cool dry place. |
The Introductction of OMEPRAZOLE
Omeprazole is a proton pump inhibitor used for the treatment of peptic ulcer and gastroesophageal reflux disease (GERD). It specifically acts on the site of the proton pump in the gastric wall cell and is converted into the active form of sulfenamide, which then irreversibly binds to the sulfhydryl group of the proton pump through the disulfide bond to produce a complex of sulfenamide and the proton pump (H+-K+-ATPase), thereby inhibiting the activity of the enzyme and preventing the transport of H+ from the wall cell into the gastric lumen, blocking the last step of gastric acid secretion, which can greatly reduce the amount of gastric acid in the gastric juice.
Omeprazole has a strong and long-lasting inhibitory effect on gastric acid secretion caused by a variety of causes (e.g., basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin and stimulation of the vagus nerve, including gastric acid secretion caused by dibutyl cyclic adenosine acid that cannot be inhibited by H2 receptor blocking drugs).
Omeprazole is used clinically to treat peptic ulcer, reflux esophagitis, Zollinger-Ellison syndrome, and eradication of Helicobacter pylori (HP) with satisfactory results.
However, it should be noted that excessive use of acid-suppressing drugs such as omeprazole can lead to a decrease in the concentration of gastric acid and weakened acidity, then the germs that enter the stomach may not be killed and enter the intestine, doubling the risk of intestinal infection with germs, then diarrhea is possible. Because of the lowered stomach acid affects digestion, which in turn affects the intestinal absorption of calcium, iron and other trace elements and vitamins, leading to calcium deficiency in the body and susceptibility to fractures.
The Application & Function of OMEPRAZOLE
Other Name of OMEPRAZOLE: LOSEC; MEPRAL; GASTROGARD; OMEPRAZOLE; Loec; Moprial; Omeprazolum;
The COA of OMEPRAZOLE
| Product | OMEPRAZOLE | Batch No | 20190410 | ||
| Date of Manufacture | 2021-04-10 | Quantity | 1000kg | ||
| Date of Certificate | 2021-04-29 | CAS No. | 73590-58-6 | ||
| Date of Expire | 2023-04-09 | Sample | 10g | ||
| Storage | Store in cool & dry place, in well-closed containers. | ||||
| Test Items | Specification | Results | |||
| Appearance | White or almost white crystalline powder | White crystalline powder | |||
| Identification |
Infrared absorption: Must similar to reference standard |
Conforms | |||
|
Ultraviolet absorption: Must similar to reference standard |
Conforms | ||||
| Test for potassium: Must be positive | Conforms | ||||
| Water | ≦ 0.5% | 0.1% | |||
| Loss on drying | ≦ 0.5% | 0.2% | |||
| Residue on Ignition | ≦ 0.2% | 0.05% | |||
| Chromatographic purity | Any individual impurity ≦ 0.2% | 0.01% | |||
| Total impurities ≦ 0.5% | 0.04% | ||||
| Heavy metals | ≦ 10 ppm | Conforms | |||
| Residual solvents | Cyclohexane ≦ 0.1% | 0.007% | |||
| Isopropyl alcohol ≦ 0.2% | 0.03% | ||||
| Assay | 98.5%~101.0% | 99.5% | |||
| Conclusion | Complies with USP30 standards. | ||||