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51-05-8 Procaine Hydrochloride Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Procaine hydrochloride
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually3-5days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram,Alibaba Assurance Order
Supply Ability: 5000kg/Month
Detail Information
CAS: 51-05-8 Mf: C13H21ClN2O2
MW: 272.77 Specification: 99%
Einecs No.: 200-077-2 Appearance: White Crystalline Powder
Sample: Available
High Light:

51-05-8 Procaine Hydrochloride Powder

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Procaine Hydrochloride Powder Api

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51-05-8 Anesthetic Powder


Product Description

51-05-8 HUMAN API LOCAL ANESTHETIC PURE POWDER 99% PROCAINE HYDROCHLORIDE

51-05-8 Procaine Hydrochloride Powder 0

Product name

PROCAINE HYDROCHLORIDEPROCAINE HCI

Appearance

White Crystalline Powder

CAS

51-05-8

MF

C13H21ClN2O2

Purity

99%

Storage

Keep in cool dry place.

51-05-8 Procaine Hydrochloride Powder 1

 

The Introductction of PROCAINE HYDROCHLORIDE

 

Procaine hydrochloride is a local anesthetic, which can temporarily block the conduction of nerve fibers and has anesthetic effect, with strong effect, low toxicity and no addiction, but it has weak penetration to skin and mucous membrane and is not suitable for surface anesthesia.


Procaine hydrochloride aqueous solution is more stable between pH 3.0 and 5.0. Therefore, when preparing procaine hydrochloride injection, it is generally necessary to add acid to adjust the pH between 3.3 and 5.5, and strictly control the sterilization temperature and time, it is appropriate to sterilize it by circulating steam at 100℃ for 30min, and pay attention to shading and airtight storage. In dilute hydrochloric acid, the aromatic primary amine in the structure of this product generates diazonium salt with sodium nitrite, and the coupling reaction occurs with alkaline β-naphthol to produce scarlet azo compound.


Procaine hydrochloride is white fine needle-like crystal or crystalline powder at room temperature, odorless, slightly bitter and numb, easily soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. The ester bond in the structure of procaine hydrochloride can be hydrolyzed to produce p-aminobenzoic acid and diethylaminoethanol, and under certain conditions, p-aminobenzoic acid can be further decarboxylated to produce toxic aniline. Procaine hydrochloride has aromatic primary amino groups in its structure, which can be easily oxidized and discolored. pH, temperature, ultraviolet light, oxygen and metal ions can accelerate oxidation and discoloration.

 

The Application & Function of PROCAINE HYDROCHLORIDE

 

Procaine hydrochloride acts on peripheral nerves to produce conduction blocking effects, relying on concentration gradients to penetrate the nerve cell membrane in a diffuse manner, blocking sodium channels at the inner side, causing the nerve cell excitation threshold to rise, losing excitability and conductivity, and blocking information transmission, which has good local anesthetic effects.

 

Procaine hydrochloride is used for infiltration anesthesia, the solution concentration is mostly 0.25%~0.5%, each time the dosage is 0.05~0.25g, not more than 1.5g per hour. for lumbar anesthesia, the amount should not exceed 0.15g per time, with 5% solution. For local intravenous anesthesia of the extremities, 0.5% solution 40-150ml. 1%-2% solution is used for nerve conduction block, and the amount should not exceed 1g at a time.

 

Other Name of PROCAINE HYDROCHLORIDE:  

2-DIETHYLAMINO-4-AMINO-BENZOATE HYDROCHLORIDE; 2-DIETHYLAMINOETHYL 4-AMINOBENZOATE HYDROCHLORIDE; 2-DIETHYLAMINOETHYL P-AMINOBENZOATE HYDROCHLORIDE; 4-AMINO-BENZOIC ACID 2-DIETHYLAMINO-ETHYL ESTER; 4-AMINOBENZOIC ACID 2-DIETHYLAMINOETHYL ESTER HYDROCHLORIDE; AKOS B006598; ART-CHEM-BB B006598; LABOTEST-BB LT00772261; NOVOCAINE HYDROCHLORIDE; P-AMINOBENZOIC ACID 2-(DIETHYLAMINO)ETHYL ESTER HYDROCHLORIDE; P-AMINOBENZOIC ACID DIETHYLAMINO-ETHYL ESTER HYDROCHLORIDE; P-AMINOBENZOYLDIETHYLAMINOETHANOL HYDROCHLORIDE; PROCAINE; PROCAINE HCL; PROCAIN HYDROCHLORIDE; TIMTEC-BB SBB001081; aminocaine; anadolor; anesthesol.

 

The COA of PROCAINE HYDROCHLORIDE

 

51-05-8 Procaine Hydrochloride Powder 2

Contact Details
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