Send Message

CAS 38304-91-5 Prevention and treatment of angina pectoris Minoxidil Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Minoxidil
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 38304-91-5 Mf: C9H15N5O
MW: 209.248 Specification: ≥98%
Einecs No.: N/A Appearance: White Crystalline Powder

Product Description

CAS 38304-91-5 Prevention and treatment of angina pectoris Minoxidil Powder

CAS 38304-91-5 Prevention and treatment of angina pectoris Minoxidil Powder 0

Product Name






Chemical Name

1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (2:1) (salt)



Empirical Formula



There is no greater than or equal to 0 in this product. A 1% component has been identified by IARC as a probable or certain human carcinogen.


Antihypertensive drugs used in refractory, primary, or renal hypertension. Used to prevent grease alopecia and animal husbandry.




The Introductction of Minoxidil:


Minoxidil(U 10858) is an antihypertensive vasodilator medication. Target: potassium channel Minoxidil, a potent antihypertensive agent, induces generalized hypertrichosis when administered systemically, or localized hair regrowth when applied topically to sites of severe alopecia areata. The pharmacologic mechanisms by which minoxidil stimulates hair growth are unknown. This study was designed to examine whether minoxidil has direct effects on neonatal murine epidermal cells in culture. In the presence of minoxidil, cultures showed a marked dose-dependent second peak of DNA synthesis 8-10 days after culture initiation. In addition, two morphologically distinct cell types appeared. Indirect immunofluorescence staining with keratin-specific antibody revealed cytoplasmic keratin fibers, suggesting the epidermal origin of these cells. Our experiments demonstrate that minoxidil can affect epidermal cells in culture by altering their growth pattern and phenotypic appearance.


The Application & Function of Minoxidil:


Clinically, as a potassium channel opening agent, it can directly relax the vascular smooth muscle, have a powerful effect of arteriole dilation, reduce peripheral resistance and blood pressure, but has no effect on volume vessels, so it can promote venous reflux. At the same time, cardiac output and heart rate can be increased due to reflex regulation and positive frequency effect, but does not cause postural hypotension.




Finite doses of minoxidil (2%, w/v) in formulations containing varying amounts of ethanol, propylene glycol (PG), and water (60:20:20, 80:20:0, and 0:80:20 by volume, respectively) were used. Minoxidil in SC (by tape stripping), appendages (by cyanoacrylate casting), and receptor fluid was determined by liquid scintillation counting. At early times (30 min, 2 h), ethanol-containing formulations (60:20:20 and 80:20:0) caused significantly greater minoxidil retention in SC and appendages, compared to the formulation lacking ethanol (0:80:20). A significant increase in minoxidil receptor penetration occurred with the PG-rich 0:80:20 formulation after 12 h [2].



The COA of Minoxidil


CAS 38304-91-5 Prevention and treatment of angina pectoris Minoxidil Powder 1




Contact Details
Marshall Liu

Phone Number : +8615691930561

WhatsApp : +8618629242069