| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Propafenone hydrochloride |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 251-867-9 | Mf: | C21H28ClNO3 |
|---|---|---|---|
| MW: | 377.905 | Specification: | ≥98% |
| Einecs No.: | N/A | Appearance: | White Powder |
CAS 34183-22-7 S Antiarrhythmic drug Propafenone hydrochloride Powder
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Product Name |
Propafenone hydrochloride |
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Function |
APIs |
|
Specification |
99%Tech |
|
Chemical Name |
1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride (1:1) |
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CAS No. |
|
|
Empirical Formula |
C21H28ClNO3 |
|
Toxicology |
Conditions to avoid: Heat, flames and sparks. |
|
Applications |
It is used for the prevention and treatment of ventricular or supraventricular ectopic beats, tachycardia, preexcitation syndrome and the prevention of ventricular fibrillation after electric shock. |
|
Package |
1kg/bag,25kg/drum |
The Introductction of Propafenone hydrochloride:
Propafenone hydrochloride is Ic sodium channel blocker, which is a broad spectrum anti-arrhythmia drug. The results of experiments in isolated animal myocardium showed that the depolarization of the contraction phase of the receiving Chemicalbook was decreased at 0.5 ~ 1μg/min, thus the conduction was prolonged, the duration of action potential and effective refractory period were also slightly prolonged, and the threshold potential of myocardial cells was increased, and the spontaneous excitability of myocardium was obviously decreased.
The Application & Function of Propafenone hydrochloride:
It is used for the prevention and treatment of ventricular or supraventricular ectopic motion, tachycardia, preexcitation syndrome and the prevention of ventricular fibrillation after electric shock
Application:
It not only acts on atria and ventricles (mainly affecting pujinye fibers, but less affecting myocardium), but also acts on the formation and conduction of excitement. Clinical data show that the treatment dose (oral 300mg and intravenous 30mg) can reduce the myocardial stress, lasting effect, increase PQ and QRS, prolong the effective refractory period of atria and atrioventricular node, it has a antagonistic effect on various types of Chemicalbook experimental arrhythmia. The antiarrhythmic effect is related to membrane stability and competitive β -blocking. It also has weak calcium antagonism (100 times weaker than verapamil), mild myocardial inhibition, increased end-diastolic blood pressure, and reduced stroke volume, all proportional to the dose. It also mildly depresses blood pressure and slows the heart rate.
The COA of Propafenone hydrochloride
