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CAS 5534-09-8 Hormone and Endocrine-regulating Drugs Beclometasone dipropionate Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Beclometasone dipropionate
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 5534-09-8 Mf: C28H37ClO7
MW: 521.042 Specification: ≥98%
Einecs No.: 226-886-0 Appearance: White Crystalline Powder

Product Description

CAS 5534-09-8 Hormone and Endocrine-regulating Drugs Beclometasone dipropionate Powder

CAS 5534-09-8 Hormone and Endocrine-regulating Drugs Beclometasone dipropionate Powder 0

Product Name

Beclometasone dipropionate





Chemical Name

9-Chloro-16-β-methyl-11-β,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-Dipropionate



Empirical Formula



The combustion produces toxic chloride fumes


Beclometasone dipropionate is a glucocortin agonist and the original drug of the free form of Beclometasone.




The Introductction of Beclometasone dipropionate:


Beclometasone dipropionate is a potent glucocorticoid agonist; it is a prodrug of the free form, beclometasone. IC50 Value: 0.2 nM (Inhibiting thymidine incorporation) [1]Target: glucocorticoid receptorin vitro: Cortisol and beclomethasone dipropionate were more potent than salbutamol in inhibiting thymidine incorporation with IC50 values of 5 nM and 0.2 nM respectively. Cortisol 100 nM led to a 16.6 +/- 6.5% reduction and beclomethasone dipropionate 3 nM led to a 17.8 +/- 5.8% reduction in cell number


The Application & Function of ​Beclometasone dipropionate:


It is a strong external use of glucocorticoid drugs, with anti-inflammatory, anti-allergic and anti-pruritus effects, can inhibit bronchial exudate, eliminate bronchial mucosa swelling, relieve bronchospasm. The vasoconstriction effect on skin is much stronger than hydrocortisone. The local anti - inflammatory effect is 5 times that of Fuxin and Fuyan pine. Lipophilic, easy to permeate, effective after 30 minutes on the affected area. 2. It has no obvious influence on body temperature and urination. Therefore, local external use will not inhibit human cortical function and the adverse reactions caused by cortical dysfunction. 3. External application can treat various inflammatory skin diseases, such as eczema, atopic dermatitis, neurodermatitis, contact dermatitis, psoriasis, pruritus and so on. Aerosol can be used for chronic and allergic asthma, allergic rhinitis and so on.




In vivo: Controlled trials involving 497 adults and children demonstrated similar clinical efficacy between nebulized BDP and either nebulized fluticasone propionate or nebulized budesonide. Meta-analyses show that BDP, like other inhaled corticosteroids, has no major influence on patient height, urinary cortisol concentration, or bone metabolism [2]. Beclometasone dipropionate (BDP) 800 microgday(-1) suspension for nebulization and budesonide (BUD) 750 microg day(-1) given by nebulization in a twice-daily regimen, and when used in addition to the usual maintenance therapy, resulted in comparable clinical efficacy across all parameters [3]. Clinical trial: Efficacy and Tolerability of Beclometasone/Formoterol Single Inhaler in Patients With Moderate to Severe Persistent Asthma.

The COA of ​Beclometasone dipropionate

CAS 5534-09-8 Hormone and Endocrine-regulating Drugs Beclometasone dipropionate Powder 1


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