CAS: | 2387-59-9 | Mf: | C5H9NO4S |
---|---|---|---|
MW: | 221.252 | Specification: | ≥98% |
Einecs No.: | N/A | Appearance: | White Powder |
High Light: | CAS 2387-59-9 Amino Acid Powder,Amino Acid Powder Carbocisteine,CAS 2387-59-9 Carbocisteine Powder |
CAS 2387-59-9 Amino acids and Protein Drugs Carbocisteine Powder
Product Name |
Carbocisteine |
Function |
APIs |
Specification |
99%Tech |
Chemical Name |
2,2-Dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamate |
CAS No. |
|
Empirical Formula |
C5H9NO4S |
Toxicology |
Slightly soluble in hot water, very slightly soluble in room temperature water, insoluble in ethanol or acetone, soluble in acid or alkali solution. |
Applications |
This product is a mucus regulator, which mainly affects the secretion of bronchial glands at the cellular level, increasing the secretion of sialomucin with low viscosity and reducing the production of Fuconucin with high viscosity, thus reducing the viscosity of sputum and making it easy to spit out. |
Package |
1kg/bag,25kg/drum |
The Introductction of Carbocisteine:
Glycolate division (Carbocisteine) as the slime thinning agent, role and bromine has the new similar, mainly affect the secretion of bronchial glands at a cellular level, can make the mucus of sticky protein disulfide bond rupture, the low viscosity of salivary mucins secretion to increase, and high viscosity fucus mucins decrease, thus reduce the viscosity of the sputum, conducive to the discharge sputum. Oral effect is fast, 4 hours after taking obvious curative effect. It is widely distributed in lung tissues and is eventually excreted in urine as prototypes and metabolites.
The Application & Function of Carbocisteine:
This product is a kind of mucus regulator, only to the symptom of expectoration has a certain effect, when using should also pay attention to cough, expectoration etiology. This product effervescent powder or effervescent tablet should be taken after dissolving in warm water. Women weigh the pros and cons of taking drugs. It had no effect on its efficacy when used with aminoglycoside, β -lactam and other antibiotics.
Application:
1. It can be used for thick sputum, difficulty in expectoration or breathing caused by chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and other diseases, as well as lung ventilation insufficiency caused by phlegm blocking the trachea. It can also be used for postoperative expectoration difficulty and pneumonia complications.
2. Used in children with non-suppurative otitis media, it has the effect of preventing deafness.
The COA of Carbocisteine:
Test Item | Specification |
Description | A white or almost white, crystalline powder, particularly insoluble in water and in alcohol. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxxides. |
Identification | A. It complies with the test for specific optical rotation |
B. The IR spectrum of the sample is concordant with the spectrum of the reference standard, Carbocisteine CRS | |
C. The principal spot in the chromatogram obtained with the test solution(b) is similar in position,color and size to the principal spot in the chromatogram obtained with the reference solution(a) | |
D. Dark red color is produced, which changes to brown and then to yellow within a few minutes | |
pH | 2.8~3.0 |
Specific optical rotation[α]D20 | -32.5° to -35.5°(on dried basis) |
State of solution (Transmittance) | Solution S is clear and colourless Not less than 96.0% |
Nihydrin-positive substances | Not more than 0.5% |
Chloride(Cl) | Not more than 0.15% |
Sulfate(SO4) | Not more than 0.030% |
Heavy metals(Pb) | Not more than 0.001% |
Loss on Drying | Not more than 0.5% |
Sulfated ash | Not more than 0.30% |
Assay | 98.5% ~ 101.0% |