| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Neomycin sulfate |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 1405-10-3 | Mf: | C23H48N6O17S |
|---|---|---|---|
| MW: | 712.72 | Specification: | ≥98% |
| Einecs No.: | 215-773-1 | Appearance: | White To Slightly Yellow Powder |
| High Light: | Cas 1405-10-3 Neomycin Sulfate Antibiotic,API Neomycin Sulfate Antibiotic,Cas 1405-10-3 Antibacterial Raw Material |
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CAS 1405-10-3 Antibiotic API Antibacterial Raw Material Neomycin sulfate
|
Product name |
Neomycin sulfate |
|
CAS |
1405-10-3 |
|
MF |
C23H48N6O17S |
|
MW |
712.72 |
|
Melting point |
>187°C (dec.) |
|
Packing |
1kg/bag,25kg/drum |
|
Payment terms |
BTC,,Paypal,Money gram |
The Introductction of Neomycin Sulphate:
Neomycin sulphate is a kind of aminoglycoside antibiotics.This product to staphylococcus aureus (methicillin sensitive strains), corynebacterium genus, e. coli, klebsiella bacteria genera, proteus and enterobacteriaceae bacteria have good antibacterial effect, for each group streptococcus, streptococcus pneumoniae, enterococcus is active.This article pseudomonas aeruginosa, oxygen resistance.Bacteria to streptomycin, kanamycin and neomycin, have a partial or total cross resistance between gentamycin.Neomycin systemic medication has significant nephrotoxicity and ototoxicity, is currently limited to oral or topical application
The Application & Function of Neomycin Sulphate:
1. Neomycin Sulphate Mainly for the treatment of trachoma,conjunctivitis,and so on.
2. Oral administration can be used to:
Neomycin Sulphate can used to Intestinal infection.
Neomycin Sulphate can also be used as an adjuvant therapy for bowel preparation before colon surgery or hepatic coma.
Neomycin Sulphate should not be used for the treatment of systemic infections.
Neomycin Sulphate mainly for the treatment of trachoma, conjunctivitis, and so on.
Application
1. Neomycin Sulphate is typically used as a topical preparation, such as Neosporin.
2. Neomycin Sulphate can also be given orally, where it is usually combined with other antibiotics.
Neomycin Sulphate is not absorbed from the gastrointestinal tract and has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. By killing bacteria in the intestinal tract, it keeps levels low and prevents hepatic encephalopathy, especially prior to GI surgery.
Neomycin Sulphate has also been used to treat small intestinal bacterial overgrowth.
Neomycin Sulphate is not given via injection,as neomycin is extremely nephrotoxic (causes kidney damage),even when compared to other aminoglycosides.The exception is when neomycin is included, in very small quantities,as a preservative in some vaccines - typically 0.025 mg per dose.
The COA of Neomycin Sulphate:
|
Testing Item |
Standard |
Result |
|
Characteristics |
A white or yellowish-white powder. Odorless or almost. Hygroscopic |
Complies
|
|
Identification (Neomycin Sulfate) |
A;B;C The positive reaction. |
Complies |
|
Solubility |
Very soluble in water, insoluble in acetone, chloroform,ether. |
Complies
|
|
Specific Rotation |
+53.5° ~ 59.0° |
58.5° |
|
Impurity A |
≤2.0% |
0.8% |
|
Impurity C |
3% ~ 15% |
Complies |
|
Any other impurity |
Not more than the area of the principal peak in the chromatogram with RS(B) (5%) |
<5% |
|
Total other impurities |
Not more than 3 times the area of the principal peak in the chromatogram with RS(B) (15%) |
<15% |
|
Acidity or alkalinity (PH) |
5.0-7.5 |
6.5 |
|
Loss on drying |
≤8.0% |
4.5% |
|
Disregard Limit |
Area of the principal peak obtained in the chromatogram with RS(B) (1%) |
Complies |
|
Sulphated Ash |
≤1.0% |
0.2% |
|
Assay (Neomycin Sulfate)
|
≥600μg /mg (DRY) |
655μg/mg DRY 647μg/mg MOIST |
