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Synthetic Ketoconazole Antifungal Medicine For Skin Infection CAS 65277-42-1

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Ketoconazole
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 65277-42-1 Mf: C26H28Cl2N4O4
MW: 531.43 Specification: ≥98%
Einecs No.: 265-667-4 Appearance: White To Light Yellow Powder
High Light:

Ketoconazole Antifungal Medicine

,

Antifungal Medicine For Skin Infection

,

CAS 65277-42-1 ketoconazole powder


Product Description

CAS 65277-42-1 Antibacterial Raw Material Ketoconazole

Synthetic Ketoconazole Antifungal Medicine For Skin Infection CAS 65277-42-1 0

CAS No.:

65277-42-1

English Name:

Ketoconazole

English Nickname:

(2R,4S)-ketoconazole /Brizoral /Onofin K /Nizral /Fitonal /MFCD00058579 /EINECS 265-667-4

Density:

1.4±0.1 g/cm3

Boiling Point:

753.4±60.0 °C at 760 mmHg

Melting Point(oC):

146°C

Molecular Formular:

C26H28Cl2N4O4

Molecular weight:

531.431

Flash Point:

409.4±32.9 °C

Exact Mass:

530.148743

PSA:

69.06000

LogP:

3.55

Appearance:

White to grayish white crystalline powder

Storage conditions:

Store in a sealed container in a cool, dry place. Must be kept away from oxidants. 2-8 o C

Vapor pressure:

0.0±2.5 mmHg at 25°C

Refractive index:

1.642

HS Code:

2933990090

 

The Introductction of Ketoconazole:

 

Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet.

 

The Application & Function of Ketoconazole:

 

Hair loss
Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treat
and rogenic alopecia.


The antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest ketoconazole shampoo used either alone or in combination with other treatments may be useful in reducing hair loss. At least one study has been performed showing that ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.


Veterinary use
Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage.

 

Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.


Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin.

 

The COA of Ketoconazole:

 

Product name:

Ketoconazole

CAS No.:

65277-42-1

MF:

C26H28Cl2N4O4

MW:

531.43

Item

Specification

Assay

>98%

Appearance

White powder

Odor

Characteristic

Taste

Characteristic

Particle Size

NLT 100% Through 80 mesh

Loss on Drying

<2.0%

Heavy metals

≤10ppm

Arsenic

≤3ppm

Lead

≤3ppm

<2.0%

Total Plate Count

≤1000cfu/g

Total Yeast & Mold

≤100cfu/g

E.Coli

Negative

Salmonella

Negative

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