| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Streptomycin sulfate |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 3810-74-0 | Mf: | C21H41N7O16S |
|---|---|---|---|
| MW: | 679.65 | Specification: | 98% |
| Einecs No.: | 223-286-0 | Appearance: | White To Off-white |
CAS 3810-74-0 Antibiotic API Anti-Inflammatory Streptomycin sulfate
|
Product Name: |
Streptomycin sulfate |
|
Synonyms: |
Verstrep;O-2-Deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1->4)-N,N'-bis(aminoiminomethyl)-D-streptamine sulfate;Strep-sol;Streptomyc;Streptomycin 2/3 Sulfate;2-[(1S,2R,3S,4S,5R,6S)-5-(diaminomethylideneamino)-2-[(2R,3S,4S,5R)-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-methylamino-oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyl-oxolan-2-yl]oxy-3,4,6-trihydroxy-cyclohexyl]guanidine;D-Streptamine, O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1->4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3);O-2-Deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-D-Streptamine sulfate (2:3) salt |
|
CAS: |
3810-74-0 |
|
MF: |
C21H41N7O16S |
|
MW: |
679.65 |
|
EINECS: |
223-286-0 |
|
Product Categories: |
Aminoglycosides (Antibiotics for Research and Experimental Use);Antibiotics for Research and Experimental Use;Biochemistry;Antibiotic Explorer;AGRI-STREP;Inhibitors;AminoglycosidesPesticides;AntibioticsPesticides&Metabolites;BactericidesAntibiotics;Intermediates & Fine Chemicals;Oligosaccharides;Pharmaceuticals;API;antibiotic;Antibiotics;BacteriostaticAlphabetic;Chemical Structure;Fungicides;Pesticides;Principle;S;SN - SZ;Peptide Synthesis/Antibiotics |
|
Mol File: |
3810-74-0.mol |
The Introductction of Streptomycin sulfate:
Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This Streptomycin sulfate antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.
The Application & Function of Streptomycin sulfate:
1. Streptomycin sulfate is effective against Gram-positive bacteria and gram-negative bacteria. But it is less effective than penicillin G in treating Gram-positive bacteria such as Streptococcus pneumoniae bacteria, and has no effects on Rickettsia, protozoa, viruses.
2. Streptomycin sulfate is effective in treating a variety of skin tuberculosis with an effect of inhibiting the proliferation of Mycobacterium tuberculosis and the production of toxin. Moreover, at high concentrations (> 0.4 μg/mL), it has bactericidal effect.
3.Streptomycin sulfate has a good effect on treating Mycobacterium tuberculosis and many kinds of gram-negative bacteria such as Escherichia.coli, Brucella, gas, influenza bacillus, Shigella, and Yersinia pestis.
4. Streptomycin sulfate is used for the treatment of Mycobacterium tuberculosis induced diseases cuh as tuberculosis, bone tuberculosis, lymphatic, intestinal tuberculosis, tuberculous meningitis and meningitis caused by susceptible strains, pneumonia, sepsis, empyema, pleurisy, peritonitis, etc.
The COA of Streptomycin sulfate:
|
Items |
Standard |
Result |
|
Appearance |
A white or almost white powder |
A white powder |
|
Identifiction |
TLC,complies |
Complies |
|
Reaction with ferric chloride solution, complies |
Complies |
|
|
Reaction with α-naphthol solution,and strong sodium hypochlorite solution,complies |
Complies |
|
|
Reaction with α-naphthol solution, complies |
Complies |
|
|
Reactions of sulfates,complies |
Complies |
|
|
Appearance of solution |
Clarity:2# max |
1# max |
|
Colour:No more intense than reference solution 3. |
5# |
|
|
PH |
4.5-7.0 |
6.2 |
|
Streptomycin B |
3.0% max |
3.0% max |
|
Loss on drying |
7.0% max |
4.8% |
|
Sulfated ash |
1.0% max |
0.4% |
|
Sulfate |
18.0%-21.5% |
19.7% |
|
Colorimetric test |
90.0%min |
99.5% |
|
Assay(dried substance) |
720 IU/mg min |
761 IU/mg |
|
Sterility |
Sterility |
Sterility |
|
Bacterial endotoxins |
0.25 IU/mg max,complies |
Complies |
|
Abnormal toxicity |
1mg/0.5ml,complies |
Complies |
|
Sodium metabisulfite |
0.3% max |
0.012% |
|
Conclusion: Complies with Ph.Eur.8.0 |
||
