| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Cefotaxime Sodium |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, , MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 64485-93-4 | Mf: | C16H16N5NaO7S2 |
|---|---|---|---|
| MW: | 477.45 | Specification: | ≥98% |
| Einecs No.: | 264-915-9 | Appearance: | White To Yellow Power |
CAS 64485-93-4 Antibiotic API Pharmaceuticals Cefotaxime Sodium
|
Product Name: |
Cefotaxime Sodium |
|
Synonyms: |
Cefotaxime:Claforan;FIR-756;(6R,7R)-7-[[(Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(acetyloxy)methyl] |
|
CAS Number: |
64485-93-4 |
|
Molecular Formular: |
C16H16N5NaO7S2 |
|
Molecular Weight: |
477.45 |
|
EINECS |
264-915-9 |
|
Melting point |
162-163 C |
|
Specific rotation |
D20 +55±2° (c = 0.8 in water) |
|
Refractive index |
61 ° (C=1, H2O) |
|
Storage condition |
2-8°C |
|
Solubility |
H2O: aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.soluble |
|
Form |
powder |
|
Color |
white to yellow |
|
Water Solubility |
Soluble in water |
|
Merck |
14,1933 |
|
stability |
Stable. Incompatible with strong oxidizing agents. |
The Introductction of Cefotaxime Sodium:
Cefotaxime is an antibiotic used to treat a number of bacterial infections. Specifically Cefotaxime Sodium is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. Cefotaxime Sodium is given either by injection into a vein or muscle .
Common side effects include nausea, allergic reactions, and inflammation at the site of injection. Other side effects may include inflammation at the site of injection and Clostridium difficile diarrhea . Cefotaxime Sodium is not recommended in people who have had previous anaphylaxis to a penicillin. Cefotaxime Sodium is relatively safe for use during pregnancy and breastfeeding. Cefotaxime Sodium is in the third-generation cephalosporin family of medications and works by interfering with the bacteria's cell wall .
The Application & Function of Cefotaxime Sodium:
Cefotaxime Sodium is a broad-spectrum antibiotic with activity against numerous gram-positive and gram-negative bacteria.Given its broad spectrum of activity, cefotaxime is used for a variety of infections.
Cefotaxime Sodiumt is the third generation and a half cephalosporin, the antibacterial spectrum is broader than cefuroxime, the effect of gram - negative bacteria is stronger, the antibacterial spectrum includes Haemophilus influenzae, Escherichia coli, salmonella Clay and and Proteus mirabilis, Nano-, staphylococcus, pneumonia, streptococcus, and so on. The clinical application is mainly used for the infection of various sensitive bacteria, such as respiratory tract, five senses, abdominal cavity, biliary tract, meningitis, gonorrhea, urinary system infection, septicemia, etc.
The COA of Cefotaxime Sodium:
|
ITEMS |
SPECIFICATION |
RESULTS |
|
Appearance |
White to pale yellow Crystalline Powder |
Passed |
|
Identification |
IR Spectrum |
Passed |
|
Clarity |
Clear |
Passed |
|
Color of Solution |
NMT 0.2(430mm,10% solution) |
Passed |
|
Specific optical rotation |
+56°~+64° |
+61° |
|
PH |
4.5~6.5 |
5.5 |
|
Loss on drying |
≤3.0% |
2.7% |
|
Chromatographic purity |
|
|
|
Sterility |
Sterile |
Passed |
|
Bacterial Endotoxins |
NMT 0.20 USP EU/mg |
Passed |
|
Particulate matter |
≥10um NMT 6000 |
Passed |
|
Assay(HPLC) |
916-964μg/mg |
940μg/mg |
|
Storage Condition |
Preserve in tight container. |
|
