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CAS 73231-34-2 Veterinary API Antibiotic HPLC Florfenicol Water Soluble Powder

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO
Model Number: Florfenicol
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: Usually7-10days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 73231-34-2 Mf: C12H14Cl2FNO4S
MW: 358.21 Specification: ≥98%
Einecs No.: 642-986-0 Appearance: White To Off-white Power
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CAS 73231-34-2 Veterinary API

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CAS 73231-34-2 API florfenicol in cats


Product Description

 CAS 73231-34-2 Veterinary API Antibiotic Florfenicol

CAS 73231-34-2 Veterinary API Antibiotic HPLC Florfenicol Water Soluble Powder 0

 

Product Name

Florfenicol

Appearance

white powder

Test

HPLC

Certificate

ISO 9001

CAS

73231-34-2

Storage Temperature

Cool Dry Place

Items

Results

Melting point

154.0°C-154.9°C

Chlorides

conform

Heavy metals

conform

Residue on ignition

0.02%

Loss on drying

0.02%

PH

6

Total impurity

0.50%

Assay

>98%

 

The Introductction of Florfenicol:

 

Florfenicol is a commonly used veterinary antibiotic with a wide antibacterial spectrum, strong antibacterial activity and low minimum inhibitory concentration (MIC). Its antibacterial effect is 15-20 times that of chloramphenicol and foxamicol. 60 minutes after feed administration, the drug concentration in the tissue can reach the peak, which can quickly control the disease. No potential aplastic anemia, suitable for large-scale farm use, mainly for the treatment of cattle respiratory diseases caused by Pasteurelli and Haemophilus. It has a good effect on bovine foot rot disease caused by fusobacterium. Also used for sensitive bacteria caused by swine, chicken infectious diseases and fish bacterial diseases.

 

The Application & Function of Florfenicol:

 

1, to pig pleurisy, streptococcus, attach red filaments, day 2, diarrhea effects.
2, to chickens of contagion rhinitis, pig, ox lung phytophthora duck respiratory infection, inflammation, RuXianYan serous disease such as effects.
3, the aquatic product categories: for bacterial enteritis sepsis, disease, red skin disease, vibrio disease, perpendicular scale disease, class nodules disease, Enoch concurrent salmonellosis, scabies disease, eel red eosinophilic disease and bullfrogs bacterial dysentery effects.

 

Florfenicol 98% is white crystall powder, odourless, taste bitter. This product in DMF dissolve easily in the dissolved in methanol in slightly soluble in glacial acetic acid in water or chloroform micro dissolve.Suitable for various kinds of various infections caused by sensitive bacteria.

Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish.
Flufenicol tightly binds to the 50S subunit on the bacterial ribosome, hinders the transpeptide reaction of the peptide acyltransferase, and thereby inhibits the extension of the peptide chain; at the same time, it selectively acts on the 70S ribosomes that make up the bacterial cell Receptors, alter and interfere with the function of peptidyltransferase, thereby double-interfering with the synthesis of bacterial proteins. Antibiotics, which have a broad spectrum of antibacterial effects by inhibiting the activity of peptide acyltransferases, have a broad antibacterial spectrum, including a variety of Gram-positive and negative bacteria and mycoplasma. Sensitive bacteria include Haemophilus bovine, porcine swine, Shigella dysenteriae, Salmonella, E. coli, pneumococcus, influenzae, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, etc.

 

The COA of Florfenicol:

 

 

Item
Standard
Result
Appearance
White or almost white crystalline powder
Almost white crystalline powder
Melting point
152-156°C
154.6-155.1°C
Specific optical rotation
-16° to -19°
-17.5°
Identification
(1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of
the standard preparation,as obtained in the assay.
Complies
(2)UV absorption Max. at 266nm.
Complies
(3)IR spectra is consistent with CRS.
Complies
PH
4.5-6.5
5.7
Chloride
0.02% max
<0.02%
Fluorides
4.8%min
4.9%
Related substances
Individual impurity not more than 0.5%
0.35%
Total impurities not more than 2.0%
0.76%
Water
0.5% max
0.13%
Residue on ignition
0.1%max
0.06%
Heavy metals
Less than or egual to 20 millionths
Less than20 millionths
Assay(C12H14Cl2FNO4S)
98.0%min

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