| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Alprostadil Pge 1 Postaglandin E1 |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 745-65-3 | Mf: | C20H34O5 |
|---|---|---|---|
| MW: | 354.49 | Specification: | 98%-99% |
| Einecs No.: | 212-017-2 | Appearance: | White Crystalline Powder |
| High Light: | CAS 745-65-3 Sexual Enhancement Powder,Sexual Enhancement Powder Postaglandin,alprostadil PGE1 Postaglandin E1 |
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CAS: 745-65-3 Sex enhancement Alprostadil Pge 1 Postaglandin
| Product Information | |
| Other Name | postaglandin E1; PGE1 |
| Assay | 99% |
| Apprearance | White to off-white powder |
| Package | 1kg/carton; 25kg/drum |
| Payment | Alipay; Western Union; TT |
| Shipment | DHL; FedEx, EMS; Air; Sea |
| Standard | USP/EP/CP/BP |
| Storage | Sealed in dark and dry place |
| Shelf Life | 2 Years |
The Introductction of Alprostadil Pge 1 Postaglandin E1:
Prostaglandin E1 (PGE1), also known as alprostadil, is a naturally occurring prostaglandin which is used as a medication. In infants with congenital heart defects, it is used by slow injection into a vein to open the ductus arteriosus until surgery can be carried out. By injection into the penis or placement in the urethra, it is used to treat erectile dysfunction.
Common side effects when given to babies include decreased breathing, fever, and low blood pressure. When used for erectile dysfunction side effects may include penile pain, bleeding at the site of injection, and prolonged erection (priapism). Prostaglandin E1 is in the vasodilator family of medications. It works by opening blood vessels by relaxing smooth muscle.
Prostaglandin E1 was isolated in 1957 and approved for medical use in the United States in 1981. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.
The Application & Function of postaglandin E1:
Alprostadil Pge 1 Postaglandin E1 is used to treat hepatitis, cirrhosis, cerebral infarction, diabetes, impotence and respiratory diseases. It has anti fibrotic effect on child a and B patients without serious liver function damage, especially child a patients. It is used to induce labor, induce labor, renal insufficiency, and treat mumps, pancreatitis, etc. Prostaglandin E1 for injection is mainly suitable for myocardial infarction, heart failure, thromboangiitis, chronic arterial occlusion, central retinal vein thrombosis, platelet protection during cardiopulmonary bypass, arteriography, vascular reconstruction, etc.
Derivatives of arachidones. It can significantly inhibit and relieve platelet aggregation and improve blood microcirculation. At the same time, it also directly acts on vascular smooth muscle and dilates arterial blood vessels. The half-life is up to 5 ~ 10 minutes. It is clinically used for anticoagulant treatment of various types of angina pectoris, reducing the area of myocardial infarction, maintaining the opening of arterial catheters in infants, systemic and pulmonary hypertension, peripheral vascular diseases and other forms of cardiopulmonary bypass. Application: it is suitable for myocardial infarction, heart failure, thromboangiitis, chronic arterial occlusion, central retinal vein thrombosis, etc.
Other Name of Alprostadil Pge 1 Postaglandin E1: ProstaglandinE1Impurity2, Prost-13-en-1-oicacid,11,15-dihydroxy-9-oxo-,(11a,13E,15S)-;(8S,11S,12S,13E,15R)-11,15-Dihydroxy-9-oxoprost-13-en-1-oicacid;ent-PGE1;AlproChemicalbookstadil(PGE1)／ProstaglandinE1;Alprostadil(PGE1);ProstaglandinE1orAIPROSTADIL;l-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoicacid;l-cyclopentaneheptanoicaci
The COA of Alprostadil Pge 1 Postaglandin E1:
| Items | Standards | Results | |
| Characteristics | White to off-white crystalline powder | White crystalline powder | |
| Identification | By IR | Complies | |
| By HPLC | Complies | ||
| Water Content | ≤ 0.50% | 0.29% | |
| Residue on Ignition | ≤ 0.50% | 0.08% | |
| Residue Solvents | Ethyl acetate: ≤4000ppm | 2334ppm | |
| Hexane: ≤200ppm | ND | ||
| Limit of prostaglandin A1, prostaglandin B1, and 13,14-dihydroprostaglandin E1 | Prostaglandin A1: ≤ 1.50% | 0.13% | |
| Prostaglandin B1: ≤ 0.10% | ND | ||
| Sum of prostaglandin B1 and 13,14-dihydroprostaglandin E1: ≤ 0.50% |
0.22% | ||
| Limit of foreign prostaglandins | Single foreign prostaglandin: ≤ 0.90% | ND | |
| Total foreign prostaglandins: ≤ 2.00% | ND | ||
| Limit of Chromium | ≤ 20ppm | ||
| Limit of Rhodium | ≤ 20ppm | ||
| Assay (HPLC basis on drying) |
95.0%~105.0% | 97.10% | |
| Reference Standard | USP33 Standard | ||
| Conclusion | The product complied to USP33 standard. | ||
| Storage | Alprostadil should be kept in a well-sealed container, protected from humidity and stored in a refrigerator (2-8ºC) immediately after received. |
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