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CAS:58-63-9 Dietary Bodybuilding supplement Inosine

Basic Information
Place of Origin: China
Brand Name: HNB
Certification: ISO, SGS
Model Number: Inosine
Minimum Order Quantity: 1KG
Price: Negotiable
Packaging Details: Carton Box or Drum
Delivery Time: Usually7-10days
Payment Terms: L/C, D/P, D/A, T/T, , MoneyGram
Supply Ability: 5000kg/Month
Detail Information
CAS: 58-63-9 Mf: C10h12n4o5
MW: 268.226 Einecs: 200-390-4
Specification: 98% Certificate: GMP/ISO9001

Product Description

CAS:58-63-9 Dietary Bodybuilding supplement Inosine

CAS:58-63-9 Dietary Bodybuilding supplement Inosine 0CAS:58-63-9 Dietary Bodybuilding supplement Inosine 1


Product Name Inosine
Synonyms Atorel;beta-D-Ribofuranoside, hypoxanthine-9;beta-Inosine;HXR;Hypoxanthine D-riboside;Hypoxanthine, 9-beta-D-ribofuranosyl-;hypoxanthined-riboside;hypoxanthinenucleoside
CAS 58-63-9
MF Atorel;beta-D-Ribofuranoside, hypoxanthine-9;beta-Inosine;HXR;Hypoxanthine D-riboside;Hypoxanthine, 9-beta-D-ribofuranosyl-;hypoxanthined-riboside;hypoxanthinenucleoside
MW 268.23
EINECS 200-390-4
Product Categories Nucleotides and Nucleosides;Antivirals for Research and Experimental Use;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Nucleotides;Inhibitors;Furans

The Introductction of Inosine


Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond.


Inosine is commonly found in tRNAs and is essential for proper translation of the genetic code in wobble base pairs. Wobble base pairs for inosine and guanine.

Knowledge of inosine metabolism has led to advances in immunotherapy in recent decades. Inosine monophosphate is oxidised by the enzyme inosine monophosphate dehydrogenase, yielding xanthosine monophosphate, a key precursor in purine metabolism. Mycophenolate mofetil is an anti-metabolite, anti-proliferative drug that acts as an inhibitor of inosine monophosphate dehydrogenase. It is used in the treatment of a variety of autoimmune diseases including granulomatosis with polyangiitis because the uptake of purine by actively dividing B cells can exceed 8 times that of normal body cells, and, therefore, this set of white cells (which cannot operate purine salvage pathways) is selectively targeted by the purine deficiency resulting from inosine monophosphate dehydrogenase (IMD) inhibition.



The Function&Application of Inosine

1. The inosine is used in the treatment of leucopenia and thrombocytopenia.
2. In the treatment of acute hepatitis and chronic hepatitis and liver cirrhosis, hepatic encephalopathy.
The inosine is used for coronary atherosclerotic heart disease (coronary heart disease), myocardial infarction, rheumatic heart disease, cor pulmonale auxiliary drug use.
The inosine is used to prevent and mitigate the schistosomiasis prevention drugs caused by the heart and the liver toxicity.
The inosine is used for eye diseases (central retinal inflammation, optic atrophy) auxiliary drug use.


The COA of Inosine


Items Specification Results
Appearance White crystalline powder Complies
Identification Positive In No.1,2,3test Complies
State of solution Transmittance Clear and colorless not less than 98.0% 99.4%
Loss on drying ≤1.00% 0.18%
Residue on ignition ≤0.2% 0.05%
Heavy metals ≤10ppm <10ppm
Other related compounds of nucleic acid Chromatographically not detectable Complies
Arsenic ≤1ppm Complies
PH 4.8 to 5.8% 5.5
Assay (on dried Product) 98%~102.0% 99.4%
Conclusion This product complies with above specifications

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